Appropriate Dose Selection - How to Optimize Clinical Drug Development

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Optimal dose individualization has become more important in improving clinical efficacy and safety, given the variability in drug response, e.g., due to concurrent illnesses or co-medications. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. The continued use of biomarkers – based on the (known) pharmacology of ...

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Optimal dose individualization has become more important in improving clinical efficacy and safety, given the variability in drug response, e.g., due to concurrent illnesses or co-medications. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. The continued use of biomarkers – based on the (known) pharmacology of ...

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  • Formats: pdf
  • ISBN: 9783540495291
  • Publication Date: 6 Mar 2007
  • Publisher: Springer Berlin Heidelberg
  • Drm Setting: DRM