Current Topics in Microbiology and Immunology

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Vogt, P. K., Syru?ek, L., Schweiger, H. G., Rott, R., Melchers, F., Maaloe, O., Koprowski, H., Koldovsky, P., Klein, J., Humphrey, J. H., Hofschneider, P. H., Henle, W., Arber, W., Falkow, S.

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The study of the genetic regulation of immune response to natural multidetermi nant immunogens was undertaken by the method of bidirectional selective breed ing of High or Low antibody responder lines of mice. Five Selections are described: Selection I, carried out for agglutinin responsiveness to sheep erythrocytes and pigeon erythrocytes alternated in each generation. Selection II, carried out...