Duloxetine: Clinical Uses, Mechanism of Action and Efficacy

The class of serotonin and noradrenaline reuptake inhibitors (or SNRIs) were introduced into clinical use as a result of the perceived short-comings of other antidepressant medications. Considerations of efficacy, side effects and tolerability have consistently indicated that there is a clinical need for agents demonstrating improvements in one or more of these domains. Since its introduction in 2...