IgG4 Related Disease: Illustrated Pathology of Novel Systemic Disease

IgG4-related disease (IgG4-RD) is an increasingly recognized and novel systemic inflammatory disorder characterized by tumefactive lesions with infiltrating IgG4-positive plasma cells. The disease affects virtually every organ system. Immunologically, plasmablasts increase in patients with IgG4-RD in which activation and dysregulation of B cells may be involved. Accurate characterization by a meth...