Influence of FOX genes on aging and aging-associated diseases

FOX genes have different regulatory functions and influence aging, carcinogenesis, neurodegeneration etc. They can directly, indirectly, via interaction with homo-, heterodimers and other factors effect its target genes and thus influence RUNX, ROBO, CREB, RELN, FOXO1, POT1, telomerase , DYRK1A, PTEN, NCAM1, VLDLR, Vitamin D and others. MiRNA modulation, alternative splicing, sumoilation, methylat...