Molybdenum Cofactors and Their role in the Evolution of Metabolic Pathways

In this brief, the authors explore and review the current knowledge regarding the role of molybdenum in the evolution of biological systems and their interaction with biogeochemical cycles. Special emphasis is placed on biological nitrogen fixation and the nitrogen element cycle.

The origin and evolution of molybdenum cofactor biosynthetic pathways as well as the evolutionary significance of molybd...