Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems

The bookpresents a new, powerful model of neuronal networks, consisting of athree-dimensional neuronal culture in which 3D neuronal networks are coupled tomicro-electrode-arrays (MEAs). It discusses the main advantages of thethree-dimensional system compared to its two-dimensional counterpart, and showsthat the network dynamics, recorded during both spontaneous and stimulatedactivity, differs betw...