Role of Clinical Studies for Pets with Naturally Occurring Tumors in Translational Cancer Research

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Traditional preclinical mouse models of cancer have been very useful for studying the biology of cancer, however they often lack key characteristics of human cancers. As a result, many novel drug candidates fail in human clinical trials despite evidence of drug efficacy in those preclinical models. Thus, researchers are seeking new approaches to augment preclinical knowledge before undertaking cli...

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Traditional preclinical mouse models of cancer have been very useful for studying the biology of cancer, however they often lack key characteristics of human cancers. As a result, many novel drug candidates fail in human clinical trials despite evidence of drug efficacy in those preclinical models. Thus, researchers are seeking new approaches to augment preclinical knowledge before undertaking cli...

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  • Formats: epub
  • ISBN: 9780309379939
  • Publication Date: 9 Dec 2015
  • Publisher: National Academies Press
  • Product language: English
  • Drm Setting: DRM