Application of Peptide-Based Prodrug Chemistry in Drug Development

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Macromolecular (specifically peptide-based) drugs could potentially be highly effective medicines. However they have a relatively short duration of action and variable therapeutic index. An example of such a peptide is Glucagon-like Peptide I which could potentially be used as a revolutionary drug for diabetes. This is because it stimulates insulin only when the blood glucose level is high thereby...

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Macromolecular (specifically peptide-based) drugs could potentially be highly effective medicines. However they have a relatively short duration of action and variable therapeutic index. An example of such a peptide is Glucagon-like Peptide I which could potentially be used as a revolutionary drug for diabetes. This is because it stimulates insulin only when the blood glucose level is high thereby...

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  • Formats: pdf
  • ISBN: 9781461448754
  • Publication Date: 18 Aug 2012
  • Publisher: Springer New York
  • Product language: English
  • Drm Setting: DRM