Medicinal chemistry

This book presents a multidisciplinary assessment of the state of science in the use of systemic delivery technologies to deliver anti-aging therapeutics now under development.

Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized.

This book describes current understandings and recent progress into a varied group of natural products.

This book offers a thorough review of the scientific research that links the consumption of grapes to better health.

Hagers Handbuch der pharmazeutischen Praxis hat sich seit dem Erscheinen der 1.

"e;About 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of different types of tissue inflammation.

Coffee is one of the most popular drinks in the world but what are the health advantages or disadvantages from consuming it?

Billions of people worldwide take medicines every day to treat important diseases.

Therapeutic macromolecules and biologics have gained increasing importance in the last decade.

This fully revised and updated new edition provides a comprehensive look at nitrite and nitrate and their effect on human health and disease.

Recent advances in genetics and brain biochemistry point to the Abeta peptide as the major culprit in causing neurodegeneration in Alzheimer's Disease (AD).

The purpose of this book is to give a concise introduction to development and analysis of pharmaceutical biologics for those in the pharmaceutical industry who are switching focus from small molecules to biologics processing, analysis, and delivery.

Written by twenty-five authors from academia, pharmaceutical industry and Pharmacopeias worldwide, this monograph covers the fundamentals and applications of Quality by Design (QbD) and Analytical Quality by Design (AQbD) in a practical and didactic manner.

The proposed volume provides both fundamental and detailed information about the computational and computational-experimental studies which improve our knowledge of how leaving matter functions, the different properties of drugs (including the calculation and the design of new ones), and the creation of completely new ways of treating numerical diseases.

This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states.

This book presents a major research program investigating signal transduction processes utilizing small molecule compound probes.

The book addresses the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.

This book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics.

Tissue engineering is a multidisciplinary field incorporating the principles of biology, chemistry, engineering, and medicine to create biological substitutes of native tissues for scientific research or clinical use.

The important role of ?

The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as an alternative to the quality-adjusted life year (QALY).

This book outlines comprehensively the main medical uses of aptamers, from diagnosis to therapeutics in fourteen chapters.

The first contribution reviews the phytochemical, chemical,and biological literature on members of the ingenane class of diterpenoids fromtheir first isolation in 1968 through 2015, highlighting unresolved issues bothcommon to phorboids and specific to ingenol derivatives.

Animal cell technology is a growing discipline of cell biology which aims not only to understand structures, functions and behaviors of differentiated animal cells but also to ascertain their abilities to be used in industrial and medical purposes.

This handbook covers the medicinal and chemical properties of Ayurvedic medicines, the plants that produce them and the currently known organic compounds that occur therein.

Medicinal chemistry is both science and art.

This book addresses the consequences of high agricultural pesticide use over the last few decades in the form of organophosphate poisoning.

This book gives an overview of pharmacoproteomics and its clinical applications, as well as the latest information on drug mechanisms at the proteome level, the relationship between proteomics and toxicity or resistance, and how proteomics aid in discovery of new drug targets.

Each year for the past three years, there have been about 50 new molecular medicines approved by the United States Food & Drug Administration (FDA), of which approximately 25% were new biopharmaceuticals.

By examining historical applications of the compounds found in plants, this five-volume series serves as a reference for quality assurance, research, product development, and regulatory guidance of the compounds found in plant-based medicines.

Historically, natural products have great relevance for the development of new drugs.

The concept of "e;vital amines"e; as essential nutrients was introduced over a century ago by Dr Casimir Funk.

Chemistry for Sustainable Development in Africa gives an insight into current Chemical research in Africa.

Working in the lab, but unsure what your results actually mean?

This volume "e;Cell Engineerring 11 - Biopharmaceutical Manufacturing: Progress, Trends and Challenges"e; is a source of the latest innovative research and technical development in biomanufacturing systems.

This book is a comprehensive text covering the research and development trends in the booming field of transition metal catalyzed oxidative cross-coupling reactions.

The book HSP70 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP70 family - one of the most studied HSP - in human diseases and disorders.

Molecules of biological interest for in-vivo and in-vitro research or diagnostics of metabolic functions and of neuro-transmission are very often labeled with iodine.

Early anthropological evidence for plant use as medicine is 60,000 years old as reported from the Neanderthal grave in Iraq.

As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression.

The perfect biochemistry study tool for the classroom and examinations!

This edited volume brings together the expertise of numerous specialists on the topic of particles - their physical, chemical, pharmacological and toxicological characteristics - when they are a component of pharmaceutical products and formulations.

It is clear today that several prostaglandins play an important role in the regulation of many of the physiological events of the reproductive organs in the human.

This volume gives an overview ofstate of the art technologies and future developments in the field ofpreclinical pharmaceutical research.

This installment in the Techniques in Life Science and Biomedicine for the Non-Expert series aims to describe ESR spectroscopy as a tool for different applications, such as Healthcare & Pharmaceutical Science, Paleontology & Geochronology and Food Science.