Medicinal chemistry

Essential oils are simply the volatile oils of plants.

This book explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues.

In the past decade there has been a worldwide evolution in evidence-based medicine that focuses on real-world Comparative Effectiveness Research (CER) to compare the effects of one medical treatment versus another in real world settings.

The book provides an overview on adoption of biotechnological approaches for the conservation, micropropagation, synseed production of various medicinal and ornamental climbers.

Medicinal chemistry is both science and art.

This book is a unique overview of insights on the genetic basis of anti-diabetic activity, chemistry, physiology, biotechnology, mode-of-action, as well as cellular mechanisms of anti-diabetic secondary metabolites from medicinal plants.

In the view of most experts pharmacology is on drugs, targets, and actions.

This volume highlights the potentials as well as the limits and challenges of human breath analysis and describes the current efforts made to advance this promising technology from bench to bed.

Antibody-drug conjugates (ADCs) represent one of the most promising and exciting areas of anticancer drug discovery.

This book is the first to be entirely devoted to the challenging art of handling membrane proteins out of their natural environment, a key process in biological and pharmaceutical research, but one plagued with difficulties and pitfalls.

The last 10 years have seen a seismic shift in therapeutic product development and testing.

The author successfully developed novel anti-HIV PD 404182 derivatives that exhibited submicromolar inhibitory activity against both HIV-1 and HIV-2.

This major reference work is a one-shot knowledge base on electroporation and the use of pulsed electric fields of high intensity and their use in biology, medicine, biotechnology, and food and environmental technologies.

Currently there are no process validation (PV) textbooks addressing the lifecycle concepts (Stage 1, 2, 3).

This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies.

This book highlights the impact of nutrients on early placentation processes and their relevance for fetal growth and pregnancy outcome.

Die Kenntnisse der Grundlagen der Chemie sind für den Mediziner unerläßlich zum Verständnis der biochemischen Prozesse bei allen wichtigen Lebensvorgängen.

Continuous pharmaceutical manufacturing is currently receiving much interest from industry and regulatory authorities, with the joint aim of allowing rapid access of novel therapeutics and existing medications to the public, without compromising high quality.

Cinnamon is the common name for the spice obtained from the dried inner bark of several species of the genus Cinnamomum in the Lauraceae family.

This book gathers selected peer-reviewed papers presented at the Second International Conference on Infectious Diseases and Nanomedicine (ICIDN), held in Kathmandu, Nepal on December 15-18, 2015.

This volume gathers a selection of original articles and reviews on timely topics about the application of Taurine in human health written by members of the International Taurine Society, including COVID-19, cancer, heart disease, and diabetes, among others.

Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product.

Oncogenic transcription factors are an increasingly important target for anticancer therapies.

In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University.

This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine.

This completely revised and updated second edition showcases the considerable progress that has taken place in this field since 2008.

Globally, millions of deaths are reported annually due to cancers, bacterial, fungal, viral and parasitic diseases, diabetes and inflammatory conditions.

This book explains the existence of the intermediate using two approaches: computational chemistry and coordination chemistry.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This book offers an authoritative review of biopharmaceuticals and their clinical relevance.

This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery.

Although the means of diagnosing and treating fungal infections have improved greatly over the last decade fungi still represent a serious threat to the health of immunocompromised and immunodeficient patients.

This volume discusses hazardous environmental micropollutants, their impacts on human health, and possible means to mitigate their associated risks.

This handbook presents recent advances and offers a comprehensive reference resource covering the developments in and applications of macrocyclic supramolecular assembly, with a focus on their construction, structural characters and biological functions.

This thesis reports the latest developments in the direct amination of various C-H bonds using an H-Zn exchange/electrophilic amination strategy.

The pharmaceutical industry is one of today's most dynamic and complex industries, involving commercialization of cutting-edge scientific research, a huge web of stakeholders (from investors to doctors), multi-stage supply chains, fierce competition in the race to market, and a challenging regulatory environment.

This book outlines how advances in the diverse scientific and engineering disciplines of synthetic biology, DNA synthesis, production of protein therapeutics, and bioinformatics have led to the commercialization of new complex biotherapeutic modalities in modern era, including monoclonal and multi-specific antibodies, antibody drug conjugates (ADC), fusion proteins, CAR-T and CRISPR technologies and applications, mRNA vaccines and more.

This volume presents the proceedings of the 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies (WC2015).

This third edition is a comprehensive and extended study about the best known approaches for preparing the main types of glycosides, covering the classic and more recent glycosylation reactions used for preparing simple and challenging glycosides currently used as potent antiviral and antineoplastic drugs, or fluorogenic substrates used for enzymatic detection in cell biology.

Sliding Filament Mechanism in Muscle Contraction: Fifty Years of Research covers the history of the sliding filament mechanism in muscle contraction from its discovery in 1954 by H.

This book on classification in biomedical image applications presents original and valuable research work on advances in this field, which covers the taxonomy of both supervised and unsupervised models, standards, algorithms, applications and challenges.

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This monograph covers a novel technology to deliver drugs and cosmetics through the skin in a minimally invasive manner.