DNA Replication: The Regulatory Mechanisms

DNA replication is a key event in the cell cycle. Althoughour knowledge is far from complete and many elusiveregulatory mechanisms still remain beyondour grasp, manyenzymes and a multiplicity of biochemical mechanismsinvolved have been discovered. Recent findings in E. colihave confirmed and yet surpassed the original hypothesis ofF. Jacob. In yeast and higher euc...