Estimands in Clinical Trials

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This book provides a comprehensive, up-to-date, and practical introduction to the estimand framework and its application in clinical trials. Since its introduction by the International Council for Harmonisation (ICH) through the E9(R1) guideline in 2019, the estimand framework has led to a significant shift in the design, conduct, analysis, and interpretation of clinical trials. By explicitly alig...
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This book provides a comprehensive, up-to-date, and practical introduction to the estimand framework and its application in clinical trials. Since its introduction by the International Council for Harmonisation (ICH) through the E9(R1) guideline in 2019, the estimand framework has led to a significant shift in the design, conduct, analysis, and interpretation of clinical trials. By explicitly alig...
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  • Formats: pdf
  • ISBN: 9783032021922
  • Publication Date: 1 Jan 2026
  • Publisher: Springer Nature Switzerland
  • Product language: English
  • Drm Setting: DRM