Function and Specificity of y/d T Cells

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Our current understanding of a/~ T cell receptor (TCR) ex­ pressing T cells advanced from function and specificity to the molecular organization ofthe TCR.We now know that the TCR a and ~ chains together express specificity for (antigenic) peptides presented by the "responder" M H C allele, thus explain­ ing the phenomenon of MHC restriction at a molecular level. Surprisingly even though our perce...
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Our current understanding of a/~ T cell receptor (TCR) ex­ pressing T cells advanced from function and specificity to the molecular organization ofthe TCR.We now know that the TCR a and ~ chains together express specificity for (antigenic) peptides presented by the "responder" M H C allele, thus explain­ ing the phenomenon of MHC restriction at a molecular level. Surprisingly even though our perce...
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  • Formats: pdf
  • ISBN: 9783642764929
  • Publication Date: 6 Dec 2012
  • Publisher: Springer Berlin Heidelberg
  • Product language: English
  • Drm Setting: DRM