Dementia and neurodegenerative diseases such as Parkinson's and Alzheimer's are becoming an increasingly important cause of medical and social concern due to the growth in the ageing population.
This book covers the latest developments in the therapeutic implications of angiogenesis, ranging from angiogenesis in the brain, angiogenesis in cancer, angiogenesis' role in atherosclerosis and heart disease as well as metabolic disorders and peripheral vascular disease.
Recombinant DNA methods are powerful, revolutionary techniques that allow the isolation of single genes in large amounts from a pool of thousands or millions of genes and the modification of these isolated genes or their regulatory regions for reintroduction into cells for expression at the RNA or protein levels.
This new series on The Biochemistry and Molecular Biology of Fishes grew out of the demand for state-of-the-art review articles in a rapidly expanding field of research.
This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development.
Statisticians have met the need to test hundreds or thousands of genomics hypotheses simultaneously with novel empirical Bayes methods that combine advantages of traditional Bayesian and frequentist statistics.
Environmental insults such as extremes of temperature, extremes of water status as well as deteriorating soil conditions pose major threats to agriculture and food security.
Laccase and Polyphenol Oxidase: Biochemistry and Biotechnological Applications, a new volume in the Foundations and Frontiers in Enzymology series, provides a thorough discussion of the laccase and polyphenol oxidase enzyme families, which play a key role in the oxidation of phenolic substrates and an important biological function in many organisms.
In response to the worldwide health problems caused by nutritional zinc deficiency, coupled with the remarkable advances in our knowledge of zinc metabolism, the author has written this monograph on the clinical effects of this important mineral.
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 50 includes comprehensive profiles of four drug compounds: Sofosbuvir, Nateglinide, Linagliptin, and Dronedarone, providing comprehensive knowledge on their physical and chemical properties, synthesis and degradation pathways, analytical techniques for identification and quantification, separation methods, and pharmacology of drug substances.
Volume 45 of the Advances in Clinical Chemistry series contains review articles of wide interest to clinical laboratory scientists and diagnostic adventurers.
New insights into modern medicine and systems biology are enabled by innovative protocols and advanced technologies in mass spectrometry-based proteomics.
This book will serve as the preeminent text book on the topic of 'base excision repair', a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes.
This book is designed to serve as a textbook for core as well as elective courses offered to undergraduate and advanced undergraduate students enrolled in chemistry.
The fifth edition includes new sections on the use of adverse outcome pathways, how climate change changes how we think about toxicology, and a new chapter on contaminants of emerging concern.
Few topics in women's medicine today are as fraught with confusion and controversy as the question of appropriate treatment for menopausal symptoms and the prevention of negative long term health outcomes common to post-menopausal women.
This book encompasses current knowledge of soil microbiomes and their potential biotechnological application for plant growth, crop yield, and soil health under the natural as well as harsh environmental conditions for sustainable agriculture.
The Encyclopaedia has been written to serve a dual functions: first, to make students of the health science aware of certain basic biochemical principles and, second to use these principles to analyze commonly occurring high-related problems in terms of their biochemical com pennants.
Here the renowned editor Evgeny Katz has chosen contributions that cover a wide range of examples and issues in implantable bioelectronics, resulting in an excellent overview of the topic.
Principles of Nucleic Acid Structure, Second Edition, provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussions of X-ray crystallography, NMR, molecular modelling and databases.
The turn of the millennium from the twentieth to the twenty-first century provides an occasion to review our understanding of a biological process, biological nitrogen fixation, that is of prime importance for the continued survival of mankind.
Demonstrates how advances in plant chemical biology can translate to field applications With contributions from a team of leading researchers and pioneers in the field, this book explains how chemical biology is used as a tool to enhance our understanding of plant biology.
In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems.
This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules.
This text presents a range of topics from the molecular events surrounding hormone actions to epidemiologic studies of the effects of environmental and occupational chemicals on reproductive organs.
This unique volume reviews the beautiful architectures and varying mechanical actions of the set of specialized cellular proteins called molecular chaperones, which provide essential kinetic assistance to processes of protein folding and unfolding in the cell.
In diesem kurzen Lehrbuch werden grundlegende wissenschaftliche und klinische Aspekte der Toxikologie dargestellt und ihre wichtigsten Inhalte, Ziele und Aufgaben beschrieben.
Incorporating a bench-top format, G Proteins: Techniques of Analysis covers essential methods - with a commitment to those techniques of proven and current utility.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.
Surface bio-contamination has become a severe problem that contributes to outbreaks of community acquired and nosocomial infections through contiguous fomite transmission of diseases.
Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible.
The study of membranes has become of high importance in the fields of biology, pharmaceutical chemistry and medicine, since much of what happens in a cell or in a virus involves biological membranes.
Biochemistry, Biophysics, and Molecular Chemistry: Applied Research and Interactions provides the background needed in biophysics and molecular chemistry and offers a great deal of advanced biophysical knowledge.
We are extremely pleased that all of the chapters in this volume provide up-to-date information on a variety of topics of interest to scientists working on membrane biology.
This book presents the technological advances in the field of mass spectrometry-based approaches for treating human diseases and diagnostics as well as the application of such approaches to study, in depth, human diseases, biomarkers discovery and validation, and to provide mechanistic insights of potential new therapeutics.
