The basic principle of all molecular genetic methods is to employ inherited, discrete and stable markers to identify genotypes that characterize individuals, populations or species.
Addition, Elimination and Substitution: Markovnikov, Hofmann, Zaitsev and Walden: Discovery and Development discusses foundational reactions in organic chemistry and their major protagonists, contributions to synthesis, and history.
Covering a wide-ranging facet of a "e;gold-standard"e; targeted mass spectrometry (MS) method for the consistent detection and accurate quantification of preselected proteins in complex biological matrices, Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics: A Comprehensive View describes:The knowledge-based development of highly efficient SRM methodology including assay workflow, selection of proteins, peptides, transitions and its validation, and quality assessmentAvailable bioinformatic tools - for both pre-acquisition method development and post-MS acquisition data analysis and data repositoriesVarious relative and absolute quantification techniquesSRM-MS' widespread applications in biomarker development and in clinical studies, as well as in the analysis of various posttranslational modifications (PTMs)Current challenges and contemporary trends to overcome those difficulties In addition,it features the historical development of modern-day mass spectrometry with its vivid applications and also covers basic MS instrumentation, ionization techniques, and various proteomics approaches.
Metal and Nutrient Transporters in Abiotic Stress focuses on the different forms of environmental stress related to heavy metal, metalloid and nutrient deficiency that have the potential to inflict major damages to crop plants, leading to a massive decrease in crop yield and productivity.
Neurotoxicity of Drugs of Abuse, Volume Eight provides carefully crafted reviews on the disruptive impact of drugs of abuse on the central nervous system.
The 3rd edition of this textbook offers clear explanations of optical spectroscopic phenomena and shows how spectroscopic techniques are used in modern chemistry, biochemistry and biophysics.
Plant Endophytes and Secondary Metabolites provides the latest insights into the essential roles of these beneficial elements in plant growth, development, stress tolerance and plant protection from soil-borne disease.
Volume 44, devoted solely to the vital research areas concerning the biogeochemistry of metals and their transport in the environment and availability to living systems, offers 9 timely and authoritative chapters on these fascinating topics by 19 internationally recognized experts.
This volume covers all aspects of melanin pigmentation, providing a concise, comprehensive picture of new knowledge gained at the frontiers of research.
Excess of homocysteine, a product of the metabolism of the essential amino acid methionine, is associated with poor health, is linked to heart and brain diseases in general human populations, and accelerates mortality in heart disease patients.
The last few years have brought about many changes in the field of marine and freshwater toxins, with advances in analytical technology and the realization that these toxins are a global issue.
Microarray technology is a major experimental tool for functional genomic explorations, and will continue to be a major tool throughout this decade and beyond.
A valuable new reference on insect behavior, this exceptional new text delves into the primary sensory communication system used by most insects -- their sense of smell.
Chemie-Basiswissen stellt in den drei Bänden AnorganischeChemie, Organische Chemie und Analytische Chemie den gesamten Wissensstoff für das Diplomchemiker-Vorexamen dar.
It has been almost 20 years since the discovery by Kohler and Milstein of the technology to produce monoclonal antibodies (MAbs), a discovery that promised revolutionary changes in research, clinical diagnosis and human therapy.
As the application of nanotechnology in the myriad disciplines of science and engineering--from agriculture, pharmaceuticals, material science, and biotechnology to sensors, electronics, and mechanical and electrical engineering--brings benefits it also can produce serious threats to human health and the environment that must be evaluated.
Endocrine Disrupting Chemicals (EDCs) have been shown to produce changes in the endocrine system of organisms, leading to increases in cancers and abnormalities in reproductive structure and function.
Building from the perspective of reproductive and developmental biology, Computational Methods for Reproductive and Developmental Toxicology provides a timely and comprehensive overview of approaches in reproductive and developmental toxicology.
The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections.
The International Hypoxia Symposium convenes biannually to bring together international experts from many fields to explore the state of the art in normal and pathophysiological responses to hypoxia.
Not many years ago, problems of membranes and transport attracted the attention of but a few dozen enthusiasts, mainly physiolo- gists who recognize~ the significance of membranes for the stabilization of the general steady state of organisms.
Volume 64 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists.
