Biochemistry

This book presents the latest knowledge on the roles of progranulin (PGRN) in normal physiology and pathology and explores the emerging significance of PGRN as a therapeutic target and biomarker in various CNS disorders, including frontotemporal lobe degeneration and other neurodegenerative diseases.

The prevalence of obesity in developed countries is fast becoming a health issue on par with infectious diseases and malnutrition.

This volume in a series on neuroscience provides an overview of the last 20 years of research into the biochemistry, physiology,pharmacology and clinical therapeutic potential of adenosine and its analogues in the nervous system.

Since the discovery of HIV-l as the etiologic agent of acquired immunodeficiency syndrome (AIDS) in the early 1980s, remarkable progress has been made in both the basic understanding of the biological processes leading to AIDS and an accelerated effort in finding new treatments.

This comprehensive monograph consists of two parts: Volume I, entitled Enzyme Catalysis, Kinetics, and Substrate Binding; and Volume II, entitled Mechanism of Enzyme Action.

This is a second edition of the book, which presents an overview of the most recent findings in the biology of neutrophils.

Ls book is an account of what physical chemistry h .

The NATO Advanced Research Workshop from which this book derives was conceived during Biotec-88, the Second Spanish Conference on Biotechnology, held at Barcelona in June 1988.

This textbook covers the scientific basics of molecular bioengineering, a new field where technology meets biology and chemistry, and the fundamental knowledge required for students to understand molecular mechanisms beyond biological phenomena.

Biophysical techniques are used in many key stages of the drug discovery process including in screening for new receptor ligands, in characterising drug mechanisms, and in validating data from biochemical and cellular assays.

The structural and chemical limitations to respiratory gas exchange existing between the ambient medium and the cell are comprehensively treated.

Alternative Methods in Neurotoxicology, Volume Nine, the latest release in this series, provides an overview of important in vitro and non-vertebrate animal models available to study the neurotoxicity of a range of toxicants of occupational and environmental relevance.

This book reviews the advances and challenges of structure-based drug design in the preclinical drug discovery process, addressing various diseases, including malaria, tuberculosis and cancer.

America's drug laws have always exerted an unequal and unfair toll on Blacks and Latinos, who are arrested more often than Whites for the possession of illegal drugs and given harsher sentences.

Nach Definition, Einteilung und Chemie werden in Band 3 Pharmakologie, Neurobiochemie/Wirkmechanismus sowie Klinik (Indikationen, Dosierung, unerwünschte Wirkungen, Interaktionen, Kontrolluntersuchungen, allgemeine Behandlungsrichtlinien) der trizyklischen und nicht-trizyklischen Antidepressiva sowie der Monoaminoxidase-Hemmer und der atypischen Antidepressiva abgehandelt.

This book focuses on neuron signaling in the regulation of metabolism and body weight, and especially on methods used in these studies.

The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data.

This timely volume highlights current knowledge concerning the role of fibronectin in human biology and medicine.

Ethik im Alltag der Medizin behandelt in 15 Beiträgen das weite Spektrum der naturwissenschaftlich-medizinischen Theorie, Forschung und Therapie in ihren Beziehungen zur Ethik.

This book is the story of the marriage of a new techl}ology, computers, with an old problem, the study of neuroanatomical structures using the light microscope.

This volume is devoted solely to the research area of metalloenzymes involving amino acid-residue and related radicals.

As the largest scale chemical reaction, photosynthesis supplies all of the organic carbon and oxygen for life on Earth.

High yields and environmental control in crop farming call for precise adaptations to local growing conditions.

Plants and plant-derived compounds and drugs are becoming more and more popular with increasing numbers of scientists researching plant analysis.

There is an increasing awareness that materials and chemicals produced from fossil fuels are not sustainable, both in terms of the pollution caused by the extraction and production processes, and the fact that there is only a finite supply of these fossil fuels.

Fluorescence is a very powerful tool for work at the frontier of cell biology, photobiology and bioinstrumentation.

This definitive text provides in-depth information on chemical, photochemical, and microbiological synthesis of carbohydrates and their derivatives.

Food and Nutritional Toxicology provides a broad overview of the chemicals in food that have the potential to produce adverse health effects.

This book explores the traditional use of Ilex paraguariensis, a plant that is widely distributed in South America.

Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood.

This volume of Current Topics in Membranes focuses on adrenergic receptor biology, beginning with a review of past successes and historical perspectives then further discussing current general trends in adrenic receptor studies in various contexts.

During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems.

Reviews in Food and Nutrition Toxicity, Volume 4 includes the most recent reviews of current issues involved in the toxicity of food and nutrients.

Modern Methods of Plant Analysis When the handbook Modern Methods of Plant Analysis was first introduced in 1954 the considerations were: 1.

This book provides a comprehensive summary of research to date in the field of stable iron isotope geochemistry.

Biomolecules are molecules that are involved in the maintenance and metabolic processes of all living organisms.

Marine systems vary in their sensitivities to perturbation.

Fatigue is an important concern for athletes at all levels, recreational sport and exercise participants, athletic coaches, personal trainers, and fitness professionals.

Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision.

This book has a broad scope and provides a comprehensive overview of the most up-to-date knowledge of the plant genus Baccharis.

More than 100 years ago, Dr Casimir Funk suggested the existence of a family of organic substances that are essential for life and thus introduced the concept of "e;vital amines"e; as essential nutrients with a specific action, requiring only minute amount with the power to cure a specific disease.

Piperonyl Butoxide contains 20 chapters contributed by world experts in the field on the properties, uses, plant metabolism, and mammalian and environmental toxicology of piperonyl butoxide.

The contributions in this volume emphasize analysis of experimental data and analytical biochemistry, with examples taken from biochemistry.

This important volume is mainly concerned with the development of methods for "e;sequencing"e; - that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA.

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Advances in Biomembranes and Lipid Self-Assembly, Volume 34, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes and lipid self-assemblies, from the micro- to the nanoscale.

This volume looks at various approaches to study the pleiotropic roles of b-arrestins (b-arrs) in the control of signal transduction, and the resulting cellular and in vivo consequences that arise.