Presents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery.
The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons.
Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment.
This volume of Progress in Molecular Biology and Translational Science introduces emerging strategies of studying RNA structure and function using nanotechnological tools.
Although in the past the Swedish anatomical schools gave one of the first impulses to the study of biorhythms, this subject has never been a favourite matter of mor- phological investigations.
Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms.
This book discusses the mathematical simulation of biological systems, with a focus on the modeling of gene expression, gene regulatory networks and stem cell regeneration.
This book summarizes ourcurrent understanding about the biology and patho-biology of cardiomyocytes anddepicts common techniques for the study of these cells.
With An Emphasis On How Important Light Is To Our Earth, This Title Explains How Light Effects Photosynthesis, How Light Travels, The Different Properties Of Light And How Both Animals And People Depend On It.
This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms.
This book focuses on the biophysical aspects of tip growth: How do physical parameters like pressure, water potential, electrical fields, or ion currents contribute to and influence this specialized and highly dynamic form of cell growth?
The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal.
Role of TRPV4 Channels in Different Organ Systems, Volume 89, the latest release in the Current Topics in Membranes series, provides an in-depth description of the role of TRPV4 ion channels in different organ systems under healthy and disease conditions.
The main function of the Leydig cells is to synthesize testosterone, but growing evidence supports the idea that Leydig cells are important in regulating the testicular immune environment.
This book discusses the mechanisms of transmembrane signal transduction during B-Cell Activation, the Regulation of Gene Expression during B-Cell Differentiation, Anti-immunoglobulin antibody induction of B-Lymphocyte activation and differentiation in vivo and in vitro, Helper signals in B-Lymphocyte differentiation, Growth and differentiation of b-cell clones in vitro, B-Cell tumors as models of lymphocyte differentiation, and Memory b-cell activation, differentiation, and isotype switching.
In 1957 Otto SCHAUMANN, one of the pionieers in pharmacological research on morphine and the first to prepare synthetic opiates, presented a mono- graph entitled "e;Morphin und morphiniihnliche Verbindungen"e; as Volume 12 of the Handbook of Experimental Pharmacology.
This comprehensive yet balanced work emphasizes the principles and rationale underlying recombinant DNA methodology while furnishing a general understanding of the experimental protocols-suggesting flexible approaches to resolving particular molecular necessities that are easily adaptable to readers' specific applications.
With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues.
Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols.
Monitoring Vesicular Trafficking in Cellular Responses to Stress - Part B, Volume 165 in the Methods in Cell Biology series, highlights new advances in the field, with this new release presenting coverage of different topics, including A novel tool for detecting lysosomal membrane permeabilization by high-throughput fluorescence microscopy, Exploring selective autophagy in Drosophila, Assessment of EGFP-Q74 degradation for the measurement of autophagic flux, Multimodal assessment of autophagy in mammalian cells with a novel, LC3-based tandem reporter, Multiplex quantification of autophagic flux by imaging flow cytometry, Monitoring autophagic flux in Caenorhabditis elegans using p62/SQST-1 reporters, High throughput screening for autophagy, and much more.
