A cell is the smallest unit of living matter that is able to function independently, consisting of protoplasm a complex living material -and made up of three basic parts, a nucleus, cytoplasm and a cell membrane.
Sabine Stubler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model.
This detailed volume explores methods and protocols that aim to increase our understanding of how cells enter a quiescent state during homeostasis and how cells exit quiescence and re-enter differentiating cell divisions to restore damaged tissues, essential for developing new approaches in regenerative medicine in the future.
Notch signaling is an evolutionarily conserved pathway in multicellular organisms that regulates cell-fate determination during development and in stem cells.
CD34+ pluripotent hematopoietic stem cells (HSCs) are generally involved in all aspects of the human system as well as in the stem cell therapeutic strategies, as in bone marrow transplantation (BMT).
This volume provides an up-to-date collection of protocols describing some of the key methods to investigate the integrated stress response (ISR), a vital evolutionarily conserved mechanism that enables eukaryotic cells to adapt to stress conditions and alter their gene expression programs.
Although blood capillaries were first observed through a flea-lens microscope by Malpighi in 1661,200 more years elapsed before the cellular nature of the vessel wall was conclusively demonstrated.
The 39 chapters in this volume consider subjects ranging from genetics, markers, and molecular biology of alcoholism, to clinical observations and treatment.
The new field of applied genetic research, genetic toxicology and mutation research investigates the muta- genicity and cancerogenicity of chemicals and other agents.
Calmodulin and Signal Transduction focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways.
Proteomics aims to study all the proteins of human and other living systems, as well as their properties to provide an integrated view of cellular processes.
In Situ hybridization allows the visualization of specific DNA/RNA sequences in individual cells in tissue sections, single cells, or chromosome preparations, and is an especially important method for studying DNA and RNA in heterogeneous cell populations.
The book is of interest to academic and industrial researchers but also clinicians who are working on inflammation related topics and would like to extend their knowledge about microarrays and the application thereof.
Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue.
Learn the funny and fascinating story of Charles Darwin and the groundbreaking discoveries that resulted from his love of the humble worm in this hilarious, illustrated children's book.
A cell is the smallest unit of living matter that is able to function independently, consisting of protoplasm a complex living material -and made up of three basic parts, a nucleus, cytoplasm and a cell membrane.
This book introduces important, new knowledge regarding formaldehyde, especially endogenous formaldehyde, revealing its many key roles in the human body.
Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila.
As a result of the molecular genetic analysis of development similar mechanisms for the regulation of gene expression are found in a wide range of organisms.
This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract.
Motility is a fundamental property of living systems, from the cytoplasmic streaming of unicellular organisms to the most highly differentiated and de- veloped contractile system of higher organisms, striated muscle.