Chemical biology

This book presents specific key natural and artificial systems that are promising biocatalysts in the areas of health, agriculture, environment and energy.

Lipids are responsible not just for constituting cellular membrane but also for storing energy, transducing signaling, and modifying proteins.

Macrophages are core components of the innate immune system.

This book covers in detail the mechanisms for how energy is managed in the human body.

This Microbiology Monographs volume covers the latest advances in laccase applications in bioremediation and waste valorisation.

Lipids are responsible not just for constituting cellular membrane but also for storing energy, transducing signaling, and modifying proteins.

In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them.

This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology.

This book provides a comprehensive, organized, and concise overview of xenobiotic metabolic enzymes and their health implications.

This book provides a comprehensive description of sterols and their novel biological roles in mammalian signaling, the book covers their biosynthesis and structure, describes sterol receptor -mediated actions, their tissue distribution and their role in disease.

This book introduces readers to industrially important enzymes and discusses in detail their structures and functions, as well as their manifold applications.

The Organizing Committee of the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases compiled a group of junior investigators to provide reviews on the topics they presented at the Puerto Vallarta Bioactive Lipids conference, as part of the book series, Advances in Experimental Medicine and Biology (AEMB).

This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology.

In August 2017, the Chemical Signals in Vertebrates (CSiV) group held its 14th triennial meeting at Cardiff University in Wales.

The Gram-positive and spore-forming Bacilli are the most dominant group of bacteria that exist in various ecological niches on the earth.

The extracellular matrix (ECM) is an acellular three-dimensional network composed of proteins, glycoproteins, proteoglycans and exopolysaccharides.

Proteomics is a well-established area of Science; yet with a strong area in constant evolution, namely sample treatment.

The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable.

In recent years, the use of bioconjugation as strategy for development of more specific and directed drugs has been widely researched.

Ethers and crown ethers are important structural parts of many man-made or natural organic materials with medicinal, agrochemical or technological attributes.

The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides.

Complex carbohydrates such as high molecular weight polysaccharides like starch and cellulose, are well known for their importance in foodstuffs, paper and wood, but their importance extends far beyond that into the biopharmaceutical, healthcare, oil and printing industries.

Applications of nucleic acids have developed recently to provide solutions for biosensors, diagnostic tools and as platforms for the assembly of complex structures.

Comprehensive Biomarker Discovery and Validation for Clinical Application provides the reader with an extensive introduction into all aspects of proteomics biomarker discovery, validation and development.

Dealing with the latest information on polysaccharide gum research, particularly focused on gum Arabic, as discussed at the World Conference on "e;New developments in Acacia Gums Research and Products"e;, this book covers the production, identification, classification and application of these important carbohydrate polymers.

The modern synthetic chemist applies all the tools available to identify the drug-like molecules with the best chances of becoming novel drugs.

Hydrogen could be the fuel of the future.

Written by an experienced and well-published individual, this unique reference source takes a forward-looking approach.

The need for information in the understanding of membrane systems has been caused by three things - an increase in computer power; methodological developments and the recent expansion in the number of researchers working on it worldwide.

Since the conceptualization of the electromagnetic spectrum and development of the magnetron, microwave energy has been utilized in many aspects and disciplines of science.

Designing artificial systems with catalytic efficiencies to rival those of natural enzymes is one of the great challenges facing science today.

Understanding the major factors determining the specificity of transmembrane transfer processes in proteins is now a hot topic in molecular bio-science.

The formation of disulfide bonds is probably the most influential modification of peptides and proteins.

The understanding, at the molecular level, of the interactions between innate and adaptive arms of the immune system is currently a hot topic, particularly to those interested in immunology - especially susceptibility to infectious diseases.

This book provides a comprehensive overview of the development of therapeutic oligonucleotides for therapeutic applications, touching on a number of additional oligonucleotides including a number of small interfering RNAs currently in various phases of clinical development.

Protein folding and aggregation is the process by which newly synthesized proteins fold into the specific three-dimensional structures defining their biologically active states.

The discovery that RNA could act as a macromolecular catalyst in the cell, signified a paradigm shift in molecular biology.

Protein-carbohydrate interactions is an exciting area of research with huge potential for development and exploration.

In the last few years there have been many exciting and innovative developments in the field of membrane protein structure and this trend is set to continue.

This book brings together recent, international contributions to the study of gluten proteins from leading experts in the field.

Starch, in its many forms, provides an essential food energy source for the world's human population.

Carbohydrate bioengineering is a rapidly expanding field with many applications in medicine and industry.

Completely revised and updated, this 2nd Edition of Reactivity and Mechanism in Organic Chemistry is an ideal introduction to the quantitative description of organic reactivity for students in undergraduate and masters chemistry programmes.

How life originated from the inanimate mixture of organic and inorganic compounds on the priomordial earth remains one of the great unknowns in science.

How life originated from the inanimate mixture of organic and inorganic compounds on the priomordial earth remains one of the great unknowns in science.

From DNA and RNA to proteins and vitamins the role of nitrogen is central in organismal metabolism.

From DNA and RNA to proteins and vitamins the role of nitrogen is central in organismal metabolism.

Authored by leading experts in the enzymology of natural product biosynthesis, this completely revised and updated edition provides a description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.

Photoaging results from chronic exposure to UV radiation and is an increasingly common clinical feature, with an aging population the clinical burden is likely to increase despite advances in our understanding of the pathology and development of improved treatments.

Antibody-drug conjugates (ADCs) represent one of the most promising and exciting areas of anticancer drug discovery.