Winner of 2016 BMA Medical Award for Basic and Clinical SciencesThe Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring.
Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science.
Originally thought to be available only to the world's wealthiest nations, genomic medicine has developed into a broad range of clinical methods and technologies whose concrete applications are also revolutionizing health systems in many of the world's resource-limited nations.
Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies.
**Selected for Doody's Core Titles(R) 2024 in Clinical Genetics**Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment.
On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human diversity and its adaptative significance through a broad and eclectic selection of representative chapters.
Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science.
Predictive Modeling of Drug Sensitivity gives an overview of drug sensitivity modeling for personalized medicine that includes data characterizations, modeling techniques, applications, and research challenges.
DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies.
Advances in Cancer Research, volume 153 provides a timely review of the biology, biochemistry, and current approaches to therapeutically target the RAS oncoprotein, the most frequently mutated oncogene family in human cancers.
**Selected for Doody's Core Titles(R) 2024 in Clinical Genetics**Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment.
Principles and Practice of Clinical Research, Fourth Edition has been thoroughly revised to provide a comprehensive look at both the fundamental principles and expanding practice of clinical research.
Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation offers overviews, methods and strategies for translating genomic medicine to clinical practice.
Twentieth Century Mouse Genetics: A Historical and Scientific Review provides a comprehensive examination of key advances in mouse genetics throughout the 20th century.
**Selected for Doody's Core Titles(R) 2024 in Clinical Genetics**Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease.
This second volume on the topic will be extremely useful for the researchers and postgraduate students working on vegetable crops with a special focus on climate change.
Advances in Genetics, Volume 108 provides the latest information on genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic.
**Selected for Doody's Core Titles(R) 2024 in Clinical Genetics**Prenatal Genetic Counseling: Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty provides a foundation for new research and a one-stop source for physicians, genetic counselors, psychologists, social workers, general practitioners, grief workers, translational researchers, and administrators seeking to work in the field of clinical genomics ethically and in full consideration of patients' psychological well-being.
Genetically Modified Plants, Second Edition, provides an updated roadmap and science-based methodology for assessing the safety of genetic modification technologies, as well as risk assessment approaches from regulators across different agroecosystems.
This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc.
Epigenetics of Stress and Stress Disorders, a new volume in the Translational Epigenetics series, examines the epigeneticmechanisms involved in modifying DNA following prolonged stress or trauma.
Biostimulants for crops from seed germination to plant development focuses on the effects and roles of natural biostimulants in every aspect of plant growth development to reduce the use of harmful chemical fertilizers and pesticides.
Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century.
Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs.
This monograph introduces current genome editing technologies-clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated (Cas) systems, transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs)-and provides an assessment of the risk of misuse of these technologies based on the following parameters: accessibility, ease of misuse, magnitude of potential harm, and imminence of potential misuse.
This book provides detailed information on methodologies used in biological, serological and nucleic acid based assays for the detection, diagnosis and management of plant viruses.
Cosmic Genetic Evolution, Volume 106 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on Panspermia, Cometary Panspermia and Origin of Life, The Efficient Lamarckian Spread of Life in the Cosmos, The Sociology of Science and Generality of the DNA/RNA/Protein Paradigm Throughout the Cosmos, The Mutagenic Source and Power of Our Own Evolution, Origin of New Emergent Coronavirus and Candida Fungal Diseases - Terrestrial or Cosmic?
Twin Research: Biology, Health, Epigenetics, and Psychology is a comprehensive, applied resource in twinning and twin studies that is grounded in the most impactful findings from twin research in recent years.
The Beans and the Peas: From Orphan to Mainstream Crops presents a comprehensive literature resource on the most important food legume crops previously known as "e;orphans,"e; but which are increasingly becoming mainstream as their production opportunities have been improved through genetic improvement and biotechnology, and their role as an important nutrient source gains urgency.
**Selected for Doody's Core Titles(R) 2024 in Clinical Genetics**Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation.
Perinatal and Developmental Epigenetics, Volume 32, a new volume in the Translational Epigenetics series, provides a thorough overview of epigenetics in the early developmental and perinatal stages, illuminating pathways for drug discovery and clinical advances.
Advances in Genetics, Volume 105, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic.
Epigenetics in Cardiovascular Disease, a new volume in the Translational Epigenetics series, offers a comprehensive overview of the epigenetics mechanisms governing cardiovascular disease development, as well as instructions in research methods and guidance in pursing new studies.
This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc.
Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions.
Genomics of Rare Diseases: Understanding Disease Genetics Using Genomic Approaches, a new volume in the Translational and Applied Genomics series, offers readers a broad understanding of current knowledge on rare diseases through a genomics lens.
Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation.
Receptor Tyrosine Kinases, Volume 147 in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research in the area of Receptor Tyrosine Kinases (RTKs) in the context of major basic science and translational advances, their importance in the development of a large number of anti-cancer drugs over the decades, and a peek into postulated advances in the coming decades for a number of RTK.
Cancer Health Equity Research, Volume 146 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Pubertal Mammary Development as a 'Susceptibility Window' for Breast Cancer Disparity, Review of Patient Navigation Interventions to Address Barriers to Participation in Cancer Clinical Trials, Racial Disparities in Ovarian Cancer Research, Mighty Men: A Faith-Based Weight Loss Intervention to Reduce Cancer Risk in African American Men, Design of a Patient Navigation Intervention to Increase Rates of Surgery among African Americans with Early-Stage Lung Cancer, and much.
Epigenetics of Stress and Stress Disorders, a new volume in the Translational Epigenetics series, examines the epigeneticmechanisms involved in modifying DNA following prolonged stress or trauma.
Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application.
