Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century.
Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs.
This monograph introduces current genome editing technologies-clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated (Cas) systems, transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs)-and provides an assessment of the risk of misuse of these technologies based on the following parameters: accessibility, ease of misuse, magnitude of potential harm, and imminence of potential misuse.
Chemogenomics is the systematic screening of targeted chemical libraries of small molecules against individual drug target families with the ultimate goal of identification of novel drugs and drug targets.
This book provides detailed information on methodologies used in biological, serological and nucleic acid based assays for the detection, diagnosis and management of plant viruses.
Cosmic Genetic Evolution, Volume 106 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on Panspermia, Cometary Panspermia and Origin of Life, The Efficient Lamarckian Spread of Life in the Cosmos, The Sociology of Science and Generality of the DNA/RNA/Protein Paradigm Throughout the Cosmos, The Mutagenic Source and Power of Our Own Evolution, Origin of New Emergent Coronavirus and Candida Fungal Diseases - Terrestrial or Cosmic?
Twin Research: Biology, Health, Epigenetics, and Psychology is a comprehensive, applied resource in twinning and twin studies that is grounded in the most impactful findings from twin research in recent years.
The Beans and the Peas: From Orphan to Mainstream Crops presents a comprehensive literature resource on the most important food legume crops previously known as "e;orphans,"e; but which are increasingly becoming mainstream as their production opportunities have been improved through genetic improvement and biotechnology, and their role as an important nutrient source gains urgency.
**Selected for Doody's Core Titles(R) 2024 in Clinical Genetics**Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation.
Perinatal and Developmental Epigenetics, Volume 32, a new volume in the Translational Epigenetics series, provides a thorough overview of epigenetics in the early developmental and perinatal stages, illuminating pathways for drug discovery and clinical advances.
Advances in Genetics, Volume 105, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic.
Epigenetics in Cardiovascular Disease, a new volume in the Translational Epigenetics series, offers a comprehensive overview of the epigenetics mechanisms governing cardiovascular disease development, as well as instructions in research methods and guidance in pursing new studies.
This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc.
Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions.
Genomics of Rare Diseases: Understanding Disease Genetics Using Genomic Approaches, a new volume in the Translational and Applied Genomics series, offers readers a broad understanding of current knowledge on rare diseases through a genomics lens.
Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation.
Receptor Tyrosine Kinases, Volume 147 in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research in the area of Receptor Tyrosine Kinases (RTKs) in the context of major basic science and translational advances, their importance in the development of a large number of anti-cancer drugs over the decades, and a peek into postulated advances in the coming decades for a number of RTK.
Cancer Health Equity Research, Volume 146 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Pubertal Mammary Development as a 'Susceptibility Window' for Breast Cancer Disparity, Review of Patient Navigation Interventions to Address Barriers to Participation in Cancer Clinical Trials, Racial Disparities in Ovarian Cancer Research, Mighty Men: A Faith-Based Weight Loss Intervention to Reduce Cancer Risk in African American Men, Design of a Patient Navigation Intervention to Increase Rates of Surgery among African Americans with Early-Stage Lung Cancer, and much.
Epigenetics of Stress and Stress Disorders, a new volume in the Translational Epigenetics series, examines the epigeneticmechanisms involved in modifying DNA following prolonged stress or trauma.
Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application.
Clinical DNA Variant Interpretation: Theory and Practice, a new volume in the Translational and Applied Genomics series, covers foundational aspects, modes of analysis, technology, disease and disorder specific case studies, and clinical integration.
Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors.
Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects.
Genomic Data Sharing: Case Studies, Challenges, and Opportunities for Precision Medicine provides a comprehensive overview of current and emerging issues in genomic data sharing.
Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine.
Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy.
Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine.
Darwin's nineteenth-century writings laid the foundations for modern studies of evolution, and theoretical developments in the mid-twentieth century fostered the Modern Synthesis.
In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics.
Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine.
Transcription Factors for Abiotic Stress Tolerance in Plants highlights advances in the understanding of the regulatory network that impacts plant health and production, providing important insights for improving plant resistance.
Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics.
Nitric Oxide in Plant Biology: An Ancient Molecule with Emerging Roles is an extensive volume which provides a broad and detailed overview of Nitric Oxide (NO) in plant biology.
Fruit Crops: Diagnosis and Management of Nutrient Constraints is the first and only resource to holistically relate fruits as a nutritional source for human health to the state-of-the-art methodologies currently used to diagnose and manage nutritional constraints placed on those fruits.
Chickpea: Crop Wild Relatives for Enhancing Genetic Gains explores aspects related to critical analysis on factors responsible for narrow genetic base of chickpea productions including domestication bottleneck, the level of diversity present in different cultivated and wild species, the uniqueness and usefulness of potential gene sources available and maintained in production systems across the globe, the level of genetic erosion both at landrace and species level over time and space etc.
Wheat and Barley Grain Biofortification addresses topics associated with the alleviation of malnutrition in globally diverse populations via wheat and barley biofortification.
Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science.
This book presents a comprehensive collection of articles illustrating the importance of microbial community structure and function for ecosystem sustainability and environmental reclamation.