With the successful mapping of the human genome, we have entered an age of unprecedented opportunity in which researchers are beginning to apply this vast repository of knowledge to the treatment of human disease.
The handling and analysis of data generated by proteomics investigations represent a challenge for computer scientists, biostatisticians, and biologists to develop tools for storing, retrieving, visualizing, and analyzing genomic data.
Nucleic Acid Testing for Human Disease describes various techniques including target and signal amplification-based NAT procedures, microarrays, bead-based multiplex assays, in situ hybridization, and SNP techniques.
While the genomic revolution has quickly led to the deposit of more than 30,000 structures in the protein data bank (PDB), less than one percent of those contributions represent membrane proteins despite the fact that membrane proteins constitute some 20 percent of all proteins.
Novel Techniques for Analyzing and Combining Data from Modern Biological StudiesBroadens the Traditional Definition of Meta-AnalysisWith the diversity of data and meta-data now available, there is increased interest in analyzing multiple studies beyond statistical approaches of formal meta-analysis.
The association of a suspect with the victim or crime scene through DNA evidence is one of the most powerful statements of complicity in a crime imaginable.
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria.
With high-quality genome sequences for the important and ubiquitous Aspergilli now available, increased opportunities arise for the further understanding of its gene function, interaction, expression, and evolution.
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory.
A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source.
In September of 2007 Gaucher Disease received a commendation in the Haematology category of the 2007 British Medical Association Medical Book Competition!
Regulation of Downstream Targets, Volume 134 in the Advances in Protein Chemistry and Structural Biology series, presents interesting chapters on topics such as Transcriptional regulatory mechanisms and signaling networks in Viral Infections, Identification of potential key genes associated with pathogenesis and prognosis of endometrial cancer based on Integrated Bioinformatics Approaches, Differential regulation of genes in stage IB pancreatic cancer associated with increased risk of metastasis, AMPK-related LKB1-downstream targets, A compilation of bioinformatic approaches to identify novel downstream targets for the detection and prophylaxis of cancer, Protein phosphatases and their targets: Critical determinants of signaling pathway in plants, and more.
Rice blast, caused by the fungal pathogen Magnaporthe grisea, is one of the most destructive rice diseases worldwide and destroys enough rice to feed more than 60 million people annually.
The domestic pig is perceived as an animal with intelligence and character and yet, in the industrialized world, the majority of people have had little or no contact with them.
Essential processes in biology such as cell and nuclear division, development, intracellular transport and physiological response, rely on the perception of environmental and intracellular signals and their transduction to subcellular targets.
Investigations on various aspects of plant-pathogen interactions have the ultimate aim of providing information that may be useful for the development of effective crop disease management systems.
Studies on the phenomenon of plant pathogenesis (disease development) have been useful to have a deep insight into the interactions between host plant and the pathogen.
Studies on molecular biology of pathogens, infection process and disease resistance, have provided information essentially required to understand the vulnerable stages at which the pathogens can be tackled effectively and to adopt novel strategies to incorporate disease resistance genes from diverse sources and /or to induce resistance of cultivars with desirable agronomic attributes using biotic or abiotic agents.
Flowering plants dominate much of the Earth's surface and yet, as sessile organisms, they must constantly resist attack by numerous voracious herbivores.
Animal welfare is attracting increasing interest worldwide, but particularly from those in developed countries, who now have the knowledge and resources to be able to improve the welfare of farm animals.
Biotechnology and Sustainable Agriculture 2006 and Beyond is a collection of papers presented at the XIth international congress of the International Association of Plant Tissue Culture & Biotechnology (IAPTC&B).
Animal welfare is attracting increasing interest worldwide, but particularly from those in developed countries, who now have the knowledge and resources to be able to offer the best management systems for their farm animals, as well as potentially being able to offer plentiful resources for companion, zoo and laboratory animals.
Ascochyta blights consistently affect large areas of grain legume production (pea, lentil, chickpea and faba bean) in all countries where they are cultivated.
Advanced biotechnologies enable breeders to produce a whole generation of new crops for specialist needs ("e;designer crops"e;), including raw materials for the energy, chemical and pharmaceutical industries.
A comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall picture of the current topics central to structural and functional genomics, proteomics, metabolomics and bioinformatics, including such hot topics as RNAi, metabolic engineering and unfolded protein response.
Phylogeography of Southern European Refugia provides the first synthesis of the remarkable diversity, evolutionary complexity, and conservation importance of the flora and fauna in the Mediterranean region, with emphasis on the three major peninsular refugia.
This book will awaken the interest of breeders, phytopathologists, environmentalists, extension services, plant virologists, entomologists and molecular biologists.
