The ciliopathies are a group of rare diseases that often affect multiple systems within the body, and are caused by defects in the function or structure of cilia.
The ciliopathies are a group of rare diseases that often affect multiple systems within the body, and are caused by defects in the function or structure of cilia.
Radioisotope therapy is an internal form of radiation used to treat cancer; it may be administered orally or intravenously and represents the nearest treatment option to the 'magic bullet', specifically targeting sites of disease whilst sparing surrounding normal tissues.
Providing clinicians with the latest developments in research, this new edition of Type 1 Diabetes is a succinct and practical guide to the diagnosis, evaluation, and management of Type 1 diabetes.
Providing clinicians with the latest developments in research, this new edition of Type 1 Diabetes is a succinct and practical guide to the diagnosis, evaluation, and management of Type 1 diabetes.
Our world and bodies are becoming increasingly polluted with chemicals capable of interfering with our hormones and thus, possibly, our present and future neural and mental health.
The nervous system has a remarkable capacity for self-reorganization, and in this first systematic analysis of the interaction between hormones and brain plasticity, Luis Miguel Garcia-Segura proposes that hormones modulate metaplasticity in the brain.
Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches.
In this fascinating book, Jacques Balthazart presents a simple description of the biological mechanisms that are involved in the determination of sexual orientation in animals and also presumably in humans.
The clinical laboratory plays a critical role in the diagnosis and management of endocrine and related metabolic disorders, which are leading causes of morbidity and mortality in children and adults.
The 3rd edition of Hormones offers a comprehensive treatment of the hormones of humans all viewed from the context of current theories of their action in the framework of our current understanding their physiological actions as well as their molecular structures, and those of their receptors.
Principles and Practice of Ovarian Tissue Cryopreservation and Transplantation provides methods and techniques of ovarian tissue harvesting and cryopreservation, including instructional videos.
Psychological and Medical Perspectives on Fertility Care and Sexual Health provides the necessary specialized training of sexual dysfunction and sex therapy to those in reproductive medicine.
Sarcopenia: Molecular Mechanism and Treatment Strategies provides answers and guidance on a disease that has serious health consequences in terms of fractures, frailty, disability and diminished quality of life.
Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery offers a compelling and thought-provoking perspective for the examination of the intriguing biology of sirtuins that ties cancer and metabolic disease together and provides a critical platform for the development of sirtuin-based novel therapeutic strategies to effectively treat cancer and metabolic disorders with precision in order to minimize any potentially detrimental clinical outcomes.
While the health consequences and mechanisms by which visceral fat causes disease are well-studied, relatively less is known about ectopic fat, its patterns of deposition and its effects on the pathoetiology of type 2 diabetes, atherosclerosis, and cardiovascular disease.
Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic.
100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world's leading experts on the pregnancy hormone and cancer marker hCG.
Hormones and Synapse, Volume 114 in the Vitamins and Hormones series, highlights advances in the field, with this new volume presenting timely topics, including how growth hormone promotes synaptogenesis, sex hormones and proteins involved in brain plasticity, corticotropin releasing factor modulates excitatory synaptic transmission, bisphenol a and memory: a role for dendritic spines, brain insulin resistance impairs hippocampal synaptic plasticity, estradiol induces synaptic rearrangements, stress and remodeling of hippocampal spine synapses, neurotrophin-3 modulates synaptic transmission, nongenomic neurosteroid modulation of hippocampal dendritic spines, neural sex steroids and hippocampal synaptic plasticity, origin of chemical synapses, neural sex steroids and hippocampal synaptic plasticity, and much more.
The Essential Charcot Neuroarthropathy: Biomechanics, Pathophysiology, and MRI Findings provides a comprehensive analysis of Charcot neuroarthropathy (or Charcot Foot) in diabetic patients.
Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance.
Vasopressin, Volume 113 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting updates on timely topics, including Diabetes Insipidus in Pregnancy, Vasopressin Inactivation: Role of Insulin-Regulated Aminopeptidase, Vasotocin and the Origins of the Vasopressin/Oxytocin Receptor Gene Family, Vasopressin V2 Receptor Ligand Recognition, Development and Therapeutic Potential of Vasopressin Synthetic Analog [V4Q5]dDAVP as a Novel Anticancer Agent, Cellular Junctions and Vasopressin, Vasopressin Actions in the Kidney Renin Angiotensin System and its Role in Hypertension and Renal Disease, Oxytocin/Vasopressin-Like Neuropeptide Signaling in Insects, and much more.
Aquaporin Regulation, Volume 112, the latest release in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters highlighting Perspectives on the evolution of aquaporin superfamily, Structure and dynamics of aquaporin-1, Selectivity and Transport in Aquaporins from Molecular Simulation Studies, Aquaporin regulation in metabolic organs, Phosphorylation of human AQP2 and its role in trafficking, Regulation of Aquaporin-2 by RNA Interference, Aquaporin Regulation: Lessons from Secretory Vesicles, CFTR Regulation of Aquaporin-mediated Water Transport, Glucocorticoid Gene Regulation of Aquaporin-7, and much more.
Diabetic Neuropathy identifies the most accurate early biomarkers of nerve damage to better understand pathophysiology and diagnose diabetic neuropathy in the clinical care of patients, and in particular, permit an accurate evaluation of future therapies in clinical trials.