Clinical and internal medicine

This book systematically reviews the most important findings on cancer immune checkpoints, sharing essential insights into this rapidly evolving yet largely unexplored research topic.

This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses.

This book will address the growing roles of epigenetics in disease pathogenesis, and review the contribution of epigenetic modifications to disease onset and progression.

This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available.

This book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins.

This book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide.

This book systemically presents the latest research on lectins, covering all the major topics in the field, including the heterocomplex of lectins and Toll-like receptors, protective versus pathogenic functions in connection with microbial infections, and novel strategies for enhancing host immunity against infectious diseases caused by viruses, bacteria, and fungi.

This book presents non-linear image enhancement approaches to mammograms as a robust computer-aided analysis solution for the early detection of breast cancer, and provides a compendium of non-linear mammogram enhancement approaches: from the fundamentals to research challenges, practical implementations, validation, and advances in applications.

This book presents a state-of-the-art report on recent advances concerning Ganoderma and where the field is going.

This book presents a comprehensive overview of important immune molecules and their structure-function relationships.

This volume provides a state-of-the-art review of the key aspects of HBV.

This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD).

This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies.

This volume covers the science of ALDH enzymes in relation to chronic disease processes and the future therapeutic potentials of targeting ALDH in these processes.

This book systematically discusses the pathogenesis, prevention, and the current and potential clinical treatment of hearing loss, as well as the latest advances in hearing research.

This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application.

This book describes the precise mechanisms by which insulin resistance and diabetes mellitus (DM) act as risk factors for Alzheimer's disease (AD).

The thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments.

This book introduces the latest optical coherence tomography (OCT) imaging and computerized automatic image analysis techniques, and their applications in the diagnosis and treatment of retinal diseases.

This book elucidates how advances in genomics research are being applied in connection with heart diseases.

This second volume continues with a focus on the state of the art in genetic eye research in Asia and the Pacific.

This volume covers the emerging area of science, Clinical Lipidomics, which is the application of lipidology to the understanding of physiological and pathophysiological changes of lipidomes, with a special focus on lipidomic profiles in human diseases.

Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila.

This book provides a comprehensive review of the major barriers to HIV cure and vaccine.

This book highlights recent technological advances, reviews and applications in the field of cardiovascular engineering, including medical imaging, signal processing and informatics, biomechanics, as well as biomaterials.

This volume covers a state-of-the-art illustration of recent discoveries concerning obesity-related fatty liver diseases and liver cancer.

This thesis describes the authors' pioneering efforts in the conceptualization and implementation of combined platinum-based immuno-chemotherapeutics, which represent a significant paradigm shift from the conventional approach of directly targeting cancer.

This book gathers selected peer-reviewed papers presented at the Second International Conference on Infectious Diseases and Nanomedicine (ICIDN), held in Kathmandu, Nepal on December 15-18, 2015.

This book provides a comprehensive overview of ZIC-family research.

This book introduces and reviews several topics for each human herpesvirus.

This book presents methodological and application research in detecting cellular and molecular biophysical properties based on atomic force microscopy (AFM) nanorobotics.

This book offers comprehensive information on all aspects of ELISA, starting with the fundamentals of the immune system.

This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases.

This thesis mainly focuses on the design and synthesis of novel multifunctional nanoprobes, investigating their feasibility for applications involving sensing, molecular imaging, and the simultaneous diagnosis and therapy of cancer.

This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer.

This book discusses recent research in innate immunity, which has revealed a large number of receptors that sense the presence of microorganisms or cellular damage in tissues.

This book offers a state-of-the-art report on recent discoveries concerning viral, bacterial, and parasite infectious cancers.

This book provides a comprehensive guide to the state-of-the-art in cardiovascular computing and highlights novel directions and challenges in this constantly evolving multidisciplinary field.

This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS).

This book focuses on nanorobotic agents and stem cells for biomedical applications.

This book highlights the current state of the art in single cell analysis, an area that involves many fields of science - from clinical hematology, functional analysis and drug screening, to platelet and microparticle analysis, marine biology and fundamental cancer research.

The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects.

This book offers an essential guide to RNA activation (RNAa), an emerging and fascinating new field.

The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice.

The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice.

This Brief introduces SuperParamagnetic Iron Oxide Nanoparticles (SPIONs), the different synthesis approaches, their applications in the field of diagnostics and treatment and finally as theranostic agents in cancer.

This brief summarizes different types of organic and inorganic nanomaterials for drug delivery in cancer therapy.

This volume provides the reader with an overview of the diverse functions of the RUNX family of genes.

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets.

This book addresses current topics concerning Landau-Kleffner Syndrome (LKS) and related central auditory disorders from the perspectives of epidemiology, diagnosis, genetics and clinical treatment.