In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology.
The application of molecular biologic methods, recognition of neurogenic inflammatory processes, and utilization of genetic knockout animals are just some of the advances in toxicology of the upper airways in recent years.
To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new, yet to be developed, and approved excipients continues to increase.
Emphasizing the impact of air toxins and contaminants on human health, this Second Edition examines the latest research from the epidemiology to the cellular mechanisms underlying cardiopulmonary responses to air pollution.
Neurotoxicology provides a thorough understanding of neurotoxicology through its integration of multilateral ideas covering several disciplines, including chemistry, biochemistry, anatomy, physiology, and pathology.
As a result of new statistical and mathematical approaches, improved visualization tools, and recognition by international regulatory groups, quantitative structure-activity relationships (QSARs) now play important roles in pharmacology for the design of new drugs as well as in toxicology and ecotoxicology for hazard identification and risk assessm
This significantly updated and expanded new edition presents the scientific foundations of inhalation research essential to the design and conduct of toxicologic studies.
Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.
"e;Offers comprehensive coverage of the latest toxicological, technological, and nutritional developments in both natural and synthetic antioxidants used in the food industry.
Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics.
This up-to-date reference includes the most recent available data and detailed case studies concerning the potential health risks of aflatoxin in the human population.
Acetaminophen Toxicity: Experimental and Clinical Advances provides detailed information on the risks of consuming the drug in various situations and effective treatments of toxicity.
Hazardous Chemicals: Overview, Toxicological Profile, Challenges, and Future Perspectives offers comprehensive coverage of hazardous chemicals and their routes of exposures, mechanism of toxicity, hazard control measures, handling and storage, emergency guidelines, and safety measures.
Hazardous Chemicals: Overview, Toxicological Profile, Challenges, and Future Perspectives offers comprehensive coverage of hazardous chemicals and their routes of exposures, mechanism of toxicity, hazard control measures, handling and storage, emergency guidelines, and safety measures.
Occupational workers frequently use, store, and dispose of toxic chemicals without knowing the possible consequences, both for the workplace and the environment.
Featuring the work of 55 leading authorities on natural toxins, this new volume highlights the diversity of chemical classes among toxins, the range of effects on biological systems, and the variety of expressions of toxicoses.
Encouraged by the medicinal success of quinine, early 19th century scientists hoped strychnine, another plant alkaloid with remarkable properties, might also become a new weapon against disease.
This volume provides a basic introduction to toxicology within a framework of chemical risk to ecosystems and to human health and forms the basis of a new approach to teaching toxicology from a broad, interdisciplinary perspective.
Beginning with a definition and explanation of scheduling of controlled substances, Pathology, Toxicogenetics, and Criminalistics of Drug Abuse covers investigative methods for all illegal drugs and several legitimate pharmaceuticals that are used illicitly, including steroids.
Every three years, worldwide forensics experts gather at the Interpol Forensic Science Symposium to exchange ideas and discuss scientific advances in the field of forensic science and criminal justice.
Featuring the work of 55 leading authorities on natural toxins, this new volume highlights the diversity of chemical classes among toxins, the range of effects on biological systems, and the variety of expressions of toxicoses.
Nonclinical Development of Biologics, Biosimilars, Vaccines and Specialty Biologics, Second Edition is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, biosimilars, vaccines, cell and gene therapies and blood products.
Nonclinical Development of Biologics, Biosimilars, Vaccines and Specialty Biologics, Second Edition is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, biosimilars, vaccines, cell and gene therapies and blood products.
This book explores how metals like cadmium, mercury, lead, aluminium, manganese, and chromium can harm our health, whether through short-term or long-term exposure.
Biomaterials, Medical Devices, and Combination Products is a single-volume guide for those responsible for-or concerned with-developing and ensuring patient safety in the use and manufacture of medical devices.
A comprehensive resource, this volume offers a tool for the management of a range of chemical substances commonly used, handled, stored, transported, and disposed of as wastes.
Functional foods and nutraceuticals, dietary supplements, and natural antioxidants have established their potential roles in the protection of human health against disease.
A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists in the pharmaceutical industry today.
Hematology data from in vivo toxicology studies remains one of the most predictive measures for human risk, as the same measurements made in pre-clinical toxicology studies can be made in early clinical trials.
Capturing the growth of the global medical device market in recent years, this practical new guide is essential for all who are responsible for ensuring safety in the use and manufacture of medical devices.
Many of the toxic effects elicited by xenobiotics can be explained at the molecular level by their interaction with receptors or by disruption or interference with receptor-mediated signal transduction pathways.