Drug Design, Volume VIII covers a critical review and new extensions of quantitative methods in drug design, the design of particular types of agents, such as synthetic sweeteners, and selective ion binding compounds.
In Silico methods to predict toxicity have become increasingly important recently, particularly in light of European legislation such as REACH and the Cosmetics Regulation.
Advances in Endogenous and Exogenous Opioids contains the proceedings of the International Narcotic Research Conference (Satellite Symposium of the 8th International Congress of Pharmacology) held in Kyoto, Japan on July 26-30, 1981.
Wind-Borne Illness from Coastal Seas: Present and Future Consequences of Toxic Marine Aerosols explores the present and future human health consequences of marine aerosol poisons carried ashore by coastal winds.
Enzymatic Basis of Detoxication, Volume II, reviews the state of knowledge on foreign compound metabolism at the level of what specific enzymes can do.
Highlighting cutting-edge research on human exposure to endocrine toxicants and the related harmful effects, this book focuses on the challenges of dealing with increasing pollution levels, increased use of synthetic chemicals, and environmental endocrine disruptors that endanger the human endocrine system and its hormones.
This monograph brings together the proceedings of a workshop held in Geneva, Switzerland in March 2000 under the joint sponsorship of the University of Sheffield and F Hoffmann La Roche Ltd.
Wildlife Toxicity Assessments for Chemicals of Military Concern is a compendium of chemical-specific toxicity information with discussions on the rationale and development of Wildlife Toxicity Reference Values (TRVs) intended for use on terrestrial wildlife for risk assessment applications.
The 9th World Congress on Animal, Plant and Microbial Toxins was sponsored by the International Society on Toxinology which recently celebrated its 25th anniversary.
Whenever radioactivity is released to the atmosphere, for example by the detonation of nuclear weapons or the testing of nuclear weapons or from nuclear reactor accidents that fraction of it which remains airborne for more than a few hours is liable to be attached to aerosol particles.
Written by leading research scientists, this book integrates current knowledge of toxicology and human health through coverage of environmental toxicants, genetic / epigenetic mechanisms, and carcinogenicity.
Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS-mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects.
Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents.
NEW YORK TIMES BESTSELLERA first of its kind, functional lifestyle guide for PCOS, complete with personal stories and nourishing recipesYou've been diagnosed with or suspect polycystic ovary syndrome (PCOS).
Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects.
Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology).
Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs.
HERBAL SUPPLEMENTS An evenhanded study of pharmacological interactions between Western drugs and herbal supplementsToday, a significant percentage of Americans turn to complementary and alternative medicine practices.
Persistent organic pollutants (POPs) and toxic elements, such as dioxins, flame retardants, lead and mercury, are substances of major concern for the food industry, the regulator and the public.
Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization.
Process-Induced Food Toxicants combines the analytical, health, and risk management issues relating to all of the currently known processing-induced toxins that may be present in common foods.
Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents.
A very handy practical book written by French doctors specialised in disaster medicine, this guide offers their core experience condensed in 50 small, easily digestible chapters.
The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil.
Neurotransmitters are usually considered to be endogenous substances that are released from neurons, act on receptor sites that are typically present on membranes of postsynaptic cells and produce a functional change in the properties of the target cell.
In Infertile Environments, Janelle Lamoreaux investigates how epigenetic research into the effects of toxic exposure conceptualizes and configures environments.
A UN report presented to the UN Human Rights Council in 2017 recognized that, "e;although pesticide use has been correlated with a rise in food production, it has had catastrophic impacts"e; on human health and the environment.
The Liver in Biology and Disease was conceived as a sequel in the series Principles of Medical Biology, whose general aim continues to be the integration of human biology and molecular cell biology into modern molecular medicine.
This book delineates how systems biology, pharmacogenomic, and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model.
Cardiac Pharmacology aims to interface basic and clinical knowledge of those interventions used or being studied for use in the treatment of heart disease.
Essentials of Toxicology for Health Protection is ideal as both a course book for students and a handbook for field professionals involved in responding to chemical incidents and local environmental concerns.
This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs.
Environmental issues such as ozone layer depletion, overpopulation, biodiversity loss, global warming, natural resource depletion, and so on affect every organism on the planet somehow.
Advances in Immunopharmacology documents the proceedings of the First International Conference on Immunopharmacology held in Brighton, England, in July 1980.
The tools for detecting false positives, false negatives, and interference in interactions when testing and monitoring therapeutic drug use For physicians monitoring a patient's progress, efficacy of treatment is often linked to a patient's response to medication.
