Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results.
Nonclinical Safety Assessment Nonclinical Safety Assessment A Guide to International Pharmaceutical Regulations Bringing a new drug to market is a costly time-consuming process.
This book illustrates the current state-of-the-art in histamine research, with a focus on the appropriate methodologies to investigate the pharmacological properties and the therapeutic exploitation of HRs and their ligands.
Complete, Authoritative, Unrivaled CollectionClin-Alert, long established as the pre-eminent source of adverse drug reaction/interaction, now brings you Clin-Alert 2000.
Specialists from a number of different disciplines have contributed to this book which presents actual basic and applied findings on Fusarium species, on their metabolites and taxonomy, in connection with pathogenicity to cereal plants and potato tubers.
Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals of all types.
Build Optimal Energy and Health in Body, Mind, and SpiritEver wondered why you re feeling out of balance, stressed-out, sick, and exhausted but still can t sleep?
Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics.
This book provides up-to-date information on some of the most important aspects of ryanodine receptor function and has been written by experts in the field.
Hydrogen bond (H-bond) effects are known: it makes sea water liquid, joins cellulose microfibrils in trees, shapes DNA into genes and polypeptide chains into wool, hair, muscles or enzymes.
Microsomes and Drug Oxidations is a record of the proceedings of the Third International Symposium on Microsomes and Drug Oxidations, held in Berlin, Germany in July 1976.
An Introduction to Ethical, Safety and Intellectual Property Rights Issues in Biotechnology provides a comprehensive look at the biggest technologies that have revolutionized biology since the early 20th century, also discussing their impact on society.
Taxaceae and Cephalotaxaceae: Biodiversity, Chemodiversity, and Pharmacotherapy accounts for the biodiversity and chemodiversity of these medicinal plants, examining and synthesizing existing research into their biology, chemistry and pharmacotherapy.
This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging.
Science lost one of its distinguished researchers in the fields of biological psychiatry and neuropsychopharmacology on March 4, 1975, with the death of Harold Himwich.
Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes The second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and potential drug targets.
A concise introduction to the study of medication utilization and safety in large populations of peopleUnderstanding Pharmacoepidemiology is a clear, engagingly written roadmap to mastering the important concepts and methods of pharmacoepidemiology.
Microbial species isolated from extreme and pristine habitats are always diverse, which indicates biomolecules secreted by these species might have importance.
Advances in Physiological Sciences, Volume 1: Regulatory Functions of the CNS: Principles of Motion and Organization covers the proceedings of the 28th International Congress of Physiological Sciences, held in Budapest in 1980.
Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients.
Green Sustainable Process for Chemical and Environmental Engineering and Science: Recent Advances in Nanocarriers covers nanocarrier synthesis techniques, as well as methods for encapsulating bioactive compounds.
Pharmacological knowledge among medical students can have a very short 'half life': students often fail not because they have failed to study, but because they have been unable to retain key knowledge and reproduce it in an exam setting.
This book describes the techniques, strategies, and drugs that have been demonstrated by well-documented randomized trials to influence survival in the perioperative setting.
This reference spotlights the immunologic aspects of applying interferon-gamma to the treatment of infectious diseases - revealing the current knowledge of the biology and potential utility of interferon-gamma.
