Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences.
Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation p
Emphasizing the role of good statistical practices (GSP) in drug research and formulation, this book outlines important statistics applications for each stage of pharmaceutical development to ensure the valid design, analysis, and assessment of drug products under investigation and establish the safety and efficacy of pharmaceutical compounds.
Aimed at those already involved in drug development or those considering entering the field, Clinical Drug Trials and Tribulations, Second Edition comprehensibly addresses the new, day-to-day challenges of drug development with valuable assessments of the areas affecting the conduction of nonclinical and clinical studies.
From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics.
This reference presents a detailed overview of approaches and techniques in the management of pain caused by tissue, nerve and central nervous system injuries, categorizing pain into a variety of syndromes and underlying mechanisms to aid the development of interventional pharmacologic measures.
For all its costs, flaws, and inequities, American health care is fundamentally rooted in a belief that treatment should be based on solid scientific research.
Interesting and important ethical questions confront researchers, regulators, institutional review boards, support personnel, and research participants committed to the ethical conduct of human subjects research at all stages of research.
Winner of the Pfizer Award from the History of Science Society "e;Contrary to legend, Ivan Pavlov (1849-1936) never trained a dog to salivate to the sound of a bell.
This book explores implicit choices made by researchers, policy makers, and funders regarding who benefits from society's investment in health research.
This book is the definitive guide to field epidemiology- the application of epidemiologic methods to unexpected health problems when a rapid, on-site investigation is necessary.
This book serves as an invaluable guide on how clinical trials are designed and run, how to interpret the results, and what to make of them in general.
Migraine is a complex neurological disorder that is characterized by a complex neurobiology, clinical features that may overlap with over 300 causes of headache, and an association with major medical illnesses and comorbid diseases.
Millions of children suffer from diseases and illnesses that do not have adequate treatment, and many other children are harmed by medicines intended to help them.
The public is bombarded daily with reports about risk factors, many conflicting with each other, others accepted as "e;scientific truth"e; for awhile, then scientifically disproved, yet others questionable that later prove to be true.
Palliative care is rapidly evolving as a multidimensional therapeutic model devoted to improving the quality of life of all patientswith life-threatening illness.
Evaluating the strength or persuasiveness of epidemiologic evidence is inherently challenging, both for those new to the field and for experienced researchers.
Over the last several decades, bioethicists have championed a bewildering variety of methods for understanding and resolving difficult ethical problems in medicine, including: principlism, wide reflective equilibrium, casuistry, feminism, virtue theory, narrative, and others.
The pharmaceutical industry is praised as a world leader in high technology innovation and the creator of products that increase both longevity and quality of life for people throughout the world.
Stem cell therapy is ushering in a new era of medicine in which we will be able to repair human organs and tissue at their most fundamental level- that of the cell.
This book is the definitive guide to field epidemiology- the application of epidemiologic methods to unexpected health problems when a rapid, on-site investigation is necessary.
When used in tandem, systematic reviews and meta-analysis-- two distinct but highly compatible approaches to research synthesis-- form a powerful, scientific approach to analyzing previous studies.
Winner of the Pfizer Award from the History of Science Society "e;Contrary to legend, Ivan Pavlov (1849-1936) never trained a dog to salivate to the sound of a bell.
Green fluorescent proteins have been floating in the ocean for more than 160 million years, but it took a curious scientist, fascinated by pinpricks of green light, to begin unlocking their potential.
Green fluorescent proteins have been floating in the ocean for more than 160 million years, but it took a curious scientist, fascinated by pinpricks of green light, to begin unlocking their potential.
Much has been written about the basic incompatibility of the dominant quantitative research model in psychotherapy and the qualitative preferences of the practitioner community providing psychotherapy.
