Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials.
Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects.
Over the past century, the majority of chemical and energy needs of our industrial society has originated from fossilized carbon sources (coal, crude oil, natural gas).
This volume details protocols on rationale design of therapeutic siRNA molecules and its encapsulation with smart vehicles to overcome the barriers to an effective administration in vivo.
Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells.
Traditional biological sensors, based on enzymatic receptors and potentiometric or amperometric transducers are well reviewed and are nowadays even included extensively in many textbooks.
Interest in the study of the biology of aging especially as it relates to humans has increased steadily in the last 50 years and continues today to be at the forefront of experimental biology.
Proper development and differentiation of B lymphocytes is es- sential to ensure that an organism has the ability to mount an effective humoral immune response against foreign antigens.
More than 150 patient cases teach you how to apply the principles of pharmacotherapy to real-world clinical practiceThe essential study companion to DiPiro s Pharmacotherapy: A Pathophysiologic Approach, 10th EditionPharmacotherapy Casebook: A Patient-Focused Approach uses 157 patient cases to help you develop the skills necessary to identify and resolve the most common drug therapy problems encountered in daily clinical practice.
This unique work presents one of the most significant organ failure condition - cardiocirculatory shock - and the prominent role of Methylene Blue (MB).
Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells.
This volume covers the science of ALDH enzymes in relation to chronic disease processes and the future therapeutic potentials of targeting ALDH in these processes.
Phenomena as diverse as tuberculin sensitivity, delayed sensitivity to soluble proteins other than tuberculin, contact allergy, homograft rejection, experimental autoallergies, and the response to many microorganisms, have been classified as members of the class of immune reactions known as delayed or cellular hypersensitivity.
Molecular epidemiology has recently broaden its focuses due to the development of molecular tools but also by incorporating advances of other fields such as mathematical epidemiology, molecular ecology, population genetics and evolution.
In addition to the traditional cytogenetics still used as the basic methodology for everyday clinical diagnosis, new molecular cytogenetic techniques provide a useful basis for routine diagnosis.
The difficulty in achieving effective translation of basic mechanistic biomedical knowledge into effective therapeutics, is the greatest challenge in biomedical research.
The inflammasome is a protein complex composed of an intracellular sensor-typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC.
Divided into five sections, Agri-Food Industry Strategies for Healthy Diets and Sustainability: New Challenges in Nutrition and Public Health provides an overview of the challenges and future perspectives related to nutrition, public health, and sustainability.
The 1st edition of Error Reduction and Prevention in Surgical Pathology was an opportunity to pull together into one place all the ideas related to errors in surgical pathology and to organize a discipline in error reduction.
A must-have guide for any professional in the drug manufacturing industry The Good Clinical Practice (GCP) audit is a tedious but necessary exercise that assures that all parties do their job properly and in compliance with the applicable FDA code.
The complexity of biological systems has intrigued scientists from many disciplines and has given birth to the highly influential field of systems biology wherein a wide array of mathematical techniques, such as flux balance analysis, and technology platforms, such as next generation sequencing, is used to understand, elucidate, and predict the functions of complex biological systems.
This textbook introduces the basics of protein structure and logically explains how to use online software to explore the information in protein structure databases.
This book follows up the debate on the future of science and technology at the Curious2022 - Future Insight Conference, the second event in this conference series initiated on the occasion of Merck's 350th anniversary.
This volume on scientific advances in critical care testing com- piles a number of clinical and laboratory studies related to criti- cally ill patients that involve new technology, therapy options, application or interpretation of new tests, patient management and cost benefits.