This book presents the latest knowledge on a broad range of topics relating to the synthesis of natural and artificial oligonucleotides with therapeutic potential.
The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models.
Ministering to Minds Diseased: A History of Psychiatric Treatment focuses on the advancements of methodologies, approaches, and techniques in the practice of psychiatry.
Critical to the accurate diagnosis of human illness is the need to distinguish clinical features that fall within the normal range from those that do not.
One of the points clearly stressed in the beginning of this book is that the essential feature of any dynamic system is change and that, where there is change, there may also be growth and evolution.
view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al.
This book provides an overview and critical discussion of the main philosophical methods that have dominated the field of bioethics since its origins in the late 1960s and early 1970s.
Essentials of Translational Pediatric Drug Development: From Past Needs to Future Opportunities provides integrated and up-to-date insights relevant for both translational researchers and clinicians active in the field of pediatric drug development.
A comprehensive introduction to behavioral and social science research methods in the health sciences Understanding and Conducting Research in the Health Sciences is designed to develop and facilitate the ability to conduct research and understand the practical value of designing, conducting, interpreting, and reporting behavioral and social science research findings in the health science and medical fields.
Microplastics and nanoplastics have been recently found in most environmental media and in living organisms, thus representing a serious health concern of yet poorly known adverse consequences.
This detailed volume presents a diverse set of methodological approaches designed to improve our understanding of bacterial infections from a wide range of bacterial species.
Eating enough food to meet nutritional needs and maintain good health and good performance in all aspects of lifeboth at home and on the jobis important for all of us throughout our lives.
That residues of pesticide and other "e;foreign"e; chemicals in food- stuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "e;Residue Reviews"e; and by the gratifying enthusiasm, sincerity, and efforts shown by all the in- dividuals from whom manuscripts have been solicited.
Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD)) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property of being infectious, sporadic or genetic in origin.
Completely revised and updated, Pharmaceutical Experimental Design and Interpretation, Second Edition explains the major methods of experimental design and evaluation such as multivariate, sequential, and principal components analysis.
This book aims to help researchers to understand the current status of new drug development in China and major events experienced in the development of new drugs.
Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome.
This book summarizes the papers presented at the symposium "e;Dynamics and Regulation of the Arterial System"e; held at Erlangen on 28-30 October 1977 in honor of Professor Erik Wetterer.
Heat Shock Proteins: Potent Mediators of Inflammation and Immunity currently provides the most up-to-date review on new mechanisms and provides exciting insights into how heat shock proteins modulates the hosts immune response.
This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy.
With over 80 information-packed chapters, Handbook for Clinical Research delivers the practical insights and expert tips necessary for successful research design, analysis, and implementation.
The forty-year Tuskegee Syphilis Study, which took place in and around Tuskegee, Alabama, from the 1930s through the 1970s, has become a profound metaphor for medical racism, government malfeasance, and physician arrogance.
