Medical research

This book gathers the proceedings of the 2018 Abel Symposium, which was held in Geiranger, Norway, on June 4-8, 2018.

From aspects of early trials to complex modeling problems, Advances in Clinical Trial Biostatistics summarizes current methodologies used in the design and analysis of clinical trials.

Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases.

In 1964, the release of Dr.

Reduce Child Obesity: A Guide to Using The Kid's Choice Program in School and at Home provides school leaders with a practical guide for applying the Kid's Choice Program (KCP), which is a school-based program to promote healthy behaviors and reduce the risk of child obesity.

This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing.

This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules.

The National Cancer Institute's (NCI) Clinical Trials Cooperative Group Program has played a key role in developing new and improved cancer therapies.

This book reviews all aspects of major depressive disorder (MDD), casting light on its neurobiological underpinnings and describing the most recent advances in management.

Tis book concentrates on atomic force microscopy (AFM), a method recently - veloped to study the surfaces of synthetic polymeric membranes.

Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes.

Neuroscience is, by definition, a multidisciplinary field: some scientists study genes and proteins at the molecular level while others study neural circuitry using electrophysiology and high-resolution optics.

Much research has focused on the basic cellular and molecular biological aspects of stem cells.

This book provides a thorough examination of the correlation between nutrition and stroke.

Statistical Thinking for Non-Statisticians in Drug Regulation, Second Edition, is a need-to-know guide to understanding statistical methodology, statistical data and results within drug development and clinical trials.

This volume thoroughly explores of the functional role of microRNAs in cancer.

Since the invention of the laser in 1960 there has been an enormous increase in the number of applications of this newly available light and its spectacular properties, and there is no end to this development in sight.

This cutting-edge reference book discusses the intervention of artificial intelligence in the fields of drug development, modified drug delivery systems, pharmaceutical technology, and medical devices development.

Modern Medicine: Biomedical Devices, Medical Gases, Radiopharmaceuticals, New Drug Discovery, Volume 2 discusses the procedures of drug approval and regulatory requirements that must be met according to the United States Food and Drug Administration (FDA), the European Medical Agency (EMA), and the Central Drug Standard Control Organization (CDSCO).

Wenn ich mit der Hand an den heißen Ofen komme, werde ich sie unter Schmerzempfindungen äußerst schnell zurückziehen, und das ist gut für mich, denn dadurch werde ich vor weiteren Ver­ brennungen bewahrt.

Charakteristische Erkrankungen des ZNS haben durch die Erhöhung des Durchschnittsalters der Bevölkerung erheblich zugenommen und damit die Forschungsaktivität auf diesem Gebiet außerordentlich intensiviert.

Part I The Nano-Scale Biological Systems in Nature; Molecular bio-motors in living cells - by T.

Collaborative approaches are becoming a key driver in drug discovery and development.

Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects.

A Guide to Methods in the Biomedical Sciences gives a basic description of common methods used in research.

Sponsor companies and CROs alike will appreciate the industry-wide analysis, practical, how-to advice, and helpful charts and checklists provided by Outsourcing in Clinical Drug Development.

The aim of this unique volume is to help medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease.

Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide.

This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes.

In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL 2 family of proteins in apoptosis, physiology and disease.

Cutting-edge coverage of stem cell biology and applicationsFeaturing contributions from leading global experts, this authoritative volume addresses all major areas of stem cell biology and their potential therapeutic applications.

Since the invention of the laser in 1960 there has been an enormous increase in the number of applications of this newly available light and its spectacular properties, and there is no end to this development in sight.

This volume reviews the broad topic of welfare in nonhuman primates under human care.

At the beginning of the 20th century, life expectancy at birth in North America and Western Europe was around 50 years of age.

Bayesian adaptive designs provide a critical approach to improve the efficiency and success of drug development that has been embraced by the US Food and Drug Administration (FDA).

Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers.

Thanks to the omnipresent computer, current statistics can include data files of many thousands of values, and can perform any exploratory analysis in less than seconds.

The focus of this textbook is on application, rather than pure knowledge transfer of the results of all chemical biological work (which would also be beyond the scope of a book).

Design and Analysis of Cross-Over Trials is concerned with a specific kind of comparative trial known as the cross-over trial, in which subjects receive different sequences of treatments.

This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity analys

This book presents a unique approach not found in any other text for those looking to improve the clinical results of refractive surgery by gaining a better understanding of corneal biomechanics and the instrumentation related to it.

Every practicing physician, surgeon, advanced practice provider, and allied health professional interacts regularly with peer-reviewed literature: either while creating it, or consuming it.

The book contains the refereed contributions from the 45th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) 2017.

Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor Immunoenvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development.

Written by a top scholar in the field, Practitioner's Guide to Using Research for Evidence-Based Practice gives essential and practical guidance on how to integrate research appraisal into evidence-based practice endeavors to ensure the best client care.