Medical research

Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high

This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication.

Introduction to Biotransport Principles is a concise text covering the fundamentals of biotransport, including biological applications of: fluid, heat, and mass transport.

Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research.

This book represents the coming together of a number of internationally renowned scholars from science, philosophy, law and social science.

Foundations of Biochemical Psychiatry provides information pertinent to the development of biochemical psychiatry, including biochemical studies of psychiatric patients before and after pharmacological intervention and genetic studies.

Medicinal Chemistry: A Look at How Drugs Are Discovered is written for those who are interested in learning how drugs are discovered.

All new medicines and devices undergo early phase trials to assess, interpret and better understand their efficacy, tolerability and safety.

Key features include: Details the role of plants for the treatment and management of cancer and diabetes Discusses the role of phytocompounds as ligands for cancer and diabetic targets Reviews plants and the potential of phytochemicals as antidiabetic and anticancer drugs Explores the green biosynthesis of nanoparticles and their treatment efficiency

Statistical Design, Monitoring, and Analysis of Clinical Trials, Second Edition concentrates on the biostatistics component of clinical trials.

The ability of DNA to exist in configurations other than its classical double-stranded form has been known for many years.

The incessant development of quantum chemistry since the appearance of the Schrodinger * equation has turned this area into a respectable branch of science with unprecedented capabilities.

In recent years, owing to the fast development of a variety of sequencing technologies in the post human genome project era, sequencing analysis of a group of target genes, entire protein coding regions of the human genome, and the whole human genome has become a reality.

Cancer genetics is a field of daunting breadth and depth.

Lipids are responsible not just for constituting cellular membrane but also for storing energy, transducing signaling, and modifying proteins.

Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood.

A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent.

Cytoscopy is a 21-chapter text that covers the significant advances in the field of cytoscopy.

This text provides a solid understanding of the various statistical topics relevant to the design, monitoring, and analysis of a clinical trial.

This volume covers all aspects of the antibiotic discovery and development process through Phase II/III.

This collection, entitled Digital Health for Predictive, Preventive, Personalized and Participatory Medicine contains the proceedings of the first International conference on digital healthtechnologies (ICDHT 2018).

The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progressively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body.

Since this book is geared to be used by varied groups of readers such as advanced students and instructors in the fields of biology and medicine, scientists and more importantly clinicians, it is considered important to provide brief accounts of the basics of DNA damage, repair, mutagenesis and cancer.

Americans praise medical technology for saving lives and improving health.

A mixed model allows the incorporation of both fixed and random variables within a statistical analysis.

The aim of this book is to equip biostatisticians and other quantitative scientists with the necessary skills, knowledge, and habits to collaborate effectively with clinicians in the healthcare field.

Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective.

Why do you taste what you taste, and what about smelling?

Every year, hundreds of thousands of healthy volunteers and patients worldwide undertake the journey through the maze that can be clinical trials.

The Science of the Brain: Function, Dysfunction and Disease is an innovative exploration into the complex interplay between brain functionality and various neurological disorders, meticulously compiled by a world-renowned researcher.

This comprehensive resource skillfully consolidates crystal engineering, the design of organic solids, and supramolecular synthons (i.

A Single Source on Parallel Synthesis for Lead OptimizationThe end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening.

Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterized by the complexity of causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures.

The Research Handbook for Health Care Professionals is the essential guide to the entire research process for students and practitioners alike.

Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines and for the testing of interventions to enhance the quality of these processes.

It is difficult to imagine anyone who has not heard of cancer.

The pharmaceutical industry is praised as a world leader in high technology innovation and the creator of products that increase both longevity and quality of life for people throughout the world.

Focuses on the prevention and treatment of missing data in longitudinal clinical trials, looking at key principles and explaining analytic methods.

Diagnostic and Therapeutic Ultrasound has recently taken an explosive growth for better safer, economic, mobile and high quality healthcare.

This book discusses the pathology of the retina, and reviews current research on the use of cell replacement therapy and short peptides to restore functional activity in retinal neurons.

This Dictionary presents a broad range of topics relevant in present-day global bioethics.

Continuing advances in biomedical research and statistical methods call for a constant stream of updated, cohesive accounts of new developments so that the methodologies can be properly implemented in the biomedical field.

The clinical laboratory is often known as a "e;black box"e; to nurses, physicians, and surgeons, but this concise book removes the veil by covering all the pertinent aspects of the clinical laboratory.

A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials.

Diagnosing and Treating Medicus Incomphensibilis is a book of case studies on revising medical writing into plain English.

Neuromuscular Function and Disorders focuses on the various processes underlying disordered neuromuscular function.

For two decades, Understanding Clinical Papers has been helping students and professionals understand the research that supports evidence-based practice.

Remarkable advances have contributed to revolutionizing the study of vertebrate vision.

The Antigens, Volume III is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression.

The book delves into the realm of biomaterials with a strong focus on sustainability, offering insights into their diverse applications in advanced therapeutics, and, diagnostics.