The incendiary untold story of Ireland's response to the most significant public health emergency of the past century, woven from a wealth of original research and dozens of interviews with ministers, politicians, public health experts, essential workers, and ordinary people on whom the crisis exacted a personal toll.
In interviews with brilliant and controversial medical researchers and practitioners, David Jay Brown reveals "e;proposed solutions for what's wrong with modern medicine, ideas about reversing the aging process and suggestions that can lead to a future in which all diseases are easily curable.
In today's world, three great classes of non-infectious diseases - the metabolic syndromes (such as type 2 diabetes and atherosclerosis), the cancers, and the neurodegenerative disorders - have risen to the fore.
Differential Oral Diagnosis in Systemic Disease focuses on oral manifestations of systemic disease, including glomerulonephritis, hepatitis, cirrhosis, and lung infection.
R for Health Technology Assessment discusses the use of proper statistical software, specifically R, to perform the whole pipeline of analytic modelling in health technology assessment (HTA).
Virtual screening can reduce costs and increase hit rates for lead discovery by eliminating the need for robotics, reagent acquisition or production, and compound storage facilities.
Presently, intensive and global attention is being devoted to "e;biotechnology"e;--the technology utilizing marvelous capacities of living things for human welfare.
Centuries ago, predicting was an enterprise entrusted to magic and fortune tellers, while today it is the domain of knowledge to which researchers and scientists contribute daily, analyzing and interpreting pathologies, trying to decode the complexity of life, represented by unresolved problems.
Statistical Thinking in Clinical Trials combines a relatively small number of key statistical principles and several instructive clinical trials to gently guide the reader through the statistical thinking needed in clinical trials.
That residues of pesticide and other "e;foreign"e; chemicals in foodstuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "e;Residue Reviews"e; and by the gratifying en- thusiasm, sincerity, and efforts shown by all the individuals from whom manuscripts have been solicited.
The handling and analysis of data generated by proteomics investigations represent a challenge for computer scientists, biostatisticians, and biologists to develop tools for storing, retrieving, visualizing, and analyzing genomic data.
Amid increasing concern for patient safety and the shutdown of prominent research operations, the need to improve protections for individuals who volunteer to participate in research has become critical.
Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies.
This book comprehensively reviews the diverse potential of microbial enzymes with therapeutic applications, covering their production, purification, and utilization.
This volume explores the latest techniques used to study neurodevelopmental diseases (NDD) that range from molecular aspects to integrated research approaches and brain imaging in living rodents.
Novel Approaches to Cancer Chemotherapy compiles theories in tumor biology, emphasizing their potential use in developing therapeutic approaches to cancer therapy.
The book Coronavirus Therapeutics Volume I provides the most comprehensive review on contemporary knowledge on the origin and structural biology and molecular aspects of Coronaviruses.
In the 8 years since the publication of the first edition of Essentials of Anatomic Pathology, great strides have been made in our understanding of diseases and neoplastic processes.
Randomised Response-Adaptive Designs in Clinical Trials presents methods for the randomised allocation of treatments to patients in sequential clinical trials.
Readers will discover the relatively new and rapidly growing field of regenerative surgery and fat grafting, valuable for numerous plastic surgery, reconstructive, and aesthetic/cosmetic essentials.
Worldwide concern in scientific, industrial, and governmental com- munities over traces of toxic chemicals in foodstuffs and in both abiotic and biotic environments has justified the present triumvirate of specialized publications in this field: comprehensive reviews, rapidly published progress reports, and archival documentations.
Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials.
view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al.
In 2010, the 5th edition of the textbook, "e;Statistics Applied to Clinical Studies"e;, was published by Springer and since then has been widely distributed.
Provides an introduction to the various statistical techniques involved in medical research and drug development with a focus on estimating the success probability of an experiment Success Probability Estimation with Applications to Clinical Trials details the use of success probability estimation in both the planning and analyzing of clinical trials and in widely used statistical tests.
How to identify optimal phase II trial designs Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both academic and industry perspectives.
This edited volume contains a selection of chapters that are an outgrowth of the - ropean Conference on Mathematical and Theoretical Biology (ECMTB05, Dresden, Germany, July 2005).
We are extremely pleased that all of the chapters in this volume provide up-to-date information on a variety of topics of interest to scientists working on membrane biology.
As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis.
Designed as a practical, succinct guide, for quick reference by clinicians with everyday questions, this title guides the reader through the range of approaches available for diagnosis, management, or prevention of hemorrhagic and thrombotic diseases or disorders.
