In response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to their flexibility and efficiency, especially during early phase development.
Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a valid inference about the objective of the trial.
In clinical trial practice, controversial statistical issues inevitably occur regardless of the compliance with good statistical practice and good clinical practice.
It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing.
This book discusses the scope and limitations of complex reconstructive surgery that few plastic surgeons master, and that the public rarely encounters, portraying both the technical challenges of advanced reconstructive microsurgery and the human connection between physician and patient as only a master surgeon can convey.
Our bodies reveal the values, priorities, anxieties, and material realities of the society in which we are situated, and in contemporary consumer societies, human bodies both reflect the defining characteristics of our time and carry the markers of social hierarchies based on categories such as gender, race, and class.
This book introduces the core knowledge and skills for comprehensive risk assessment and management in healthcare settings and applies relevant ethical and legal principles.
Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable and non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions.
Psychotherapy in the Age of Political Polarization is a response to the challenge so many mental health professionals face: How do we best assist our clients who are suffering from the political polarization that is pervasive in our culture?
Sir Donald Irvine asks what further changes have to be made to the culture and regulation of medicine to make it as trustworthy as the public today expects.
Whether initiated by injury or disease, induced and sustained by changes in the nervous system, or manifested by society and culture, chronic pain can change one's first-person experience of the body and the world, and ultimately impacts cognitions, emotions, and behavior.
This book provides an introduction to ethics, research design as the most important part of the qualitative research process, the importance of theoretical frameworks and the relationship between the researcher and the researched in the qualitative research process.
'A page-turner with a mystery to solve, and a meditation on what it means for a child to know their parents' - Cathy Rentzenbrink'An exceptional, entirely unpredictable, real-life thriller' - Michael Mansfield'An astonishingly original memoir about truth, identity and the ethics of science' The Telegraph'Gripping' The TimesWINNER OF THE BRIDPORT PRIZE FOR MEMOIRWhat would you do to find out the truth about someone you love?
Dieses essential bietet einen Überblick über vorliegende Forschungsdaten zu den Gründen des Schwangerschaftskonflikts und präsentiert eine detaillierte aktuelle Studie sowie den zugehörigen standardisierten Erfassungsansatz.
Dieses essential bietet einen Überblick über vorliegende Forschungsdaten zu den Gründen des Schwangerschaftskonflikts und präsentiert eine detaillierte aktuelle Studie sowie den zugehörigen standardisierten Erfassungsansatz.
New Directions in Sex Therapy: Innovations and Alternatives, Third Edition focuses on new and cutting-edge therapy paradigms as alternatives to conventional clinical strategies, challenging practitioners to expand our thinking about how to deal with sexual concerns.
Sir Donald Irvine asks what further changes have to be made to the culture and regulation of medicine to make it as trustworthy as the public today expects.
Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing.
Our bodies reveal the values, priorities, anxieties, and material realities of the society in which we are situated, and in contemporary consumer societies, human bodies both reflect the defining characteristics of our time and carry the markers of social hierarchies based on categories such as gender, race, and class.
The Psychology of Eating is the essential multidisciplinary introduction to the psychology of eating, looking at the biological, genetic, developmental, and social determinants of how humans find and assimilate food.
There are numerous advantages to using Bayesian methods in diagnostic medicine, which is why they are employed more and more today in clinical studies.
Nearly every medical school around the world teaches a class about the clinical foundations of medicine and how to start the process of becoming a skilled and caring physician.
This step-by-step guide takes the reader through the complex process of investigating serious incidents in health, social care, and criminal justice environments, acknowledging differences of culture and context that shape an investigation.
This step-by-step guide takes the reader through the complex process of investigating serious incidents in health, social care, and criminal justice environments, acknowledging differences of culture and context that shape an investigation.