Recent analyses of drug attrition rates reveal that a significant number of drug candidates fail in the later stage of clinical development owing to absorption, distribution, metabolism, elimination (ADME), and toxicity issues.
Contemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology.
Drugs of Abuse: Neurological Reviews and Protocols is intended to provide insightful reviews of key current topics and, particularly, state-- the-art methods for examining drug actions in their various neuroanato- cal, neurochemical, neurophysiological, neuropharmacological, and molecular perspectives.
Molecular biology has transformed prenatal diagnosis because it permits an accurate diagnosis to be made from very small quantities of fetal material, even single cells.
Chronic pain is a complex phenomenon, which continues to remain undertreated in the majority of affected patients thus representing a significant unmet medical need, but the development of cellular, subcellular, and molecular methods of approaching this epidemic of pain shows great promise.
In past decades, the area of bioinformatics has proved to be both dynamic and vital, producing a wide spectrum of novel approaches and assuming an increasingly important role in modern bio-technological development.
The aim of the two-volume set of Placenta and Trophoblast: Methods and Protocols is to offer contemporary approaches for studying the biology of the placenta.
A cutting-edge collection of readily reproducible in vitro and in vivo methods to elucidate the mechanisms associated with cannabinoid function in health and disease.
A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals.
The COVID-19 pandemic has had a disproportionate impact on older adults with mental illness, and Geriatric Mental Health Care was conceived in response.
The recent revolution in the biological sciences and bioengineering, along with the advancements of modern design and manufacturing, biomaterials, biology, and biomedicine, have brought about the new field of computer-aided tissue engineering.
A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates.
Recent analyses of drug attrition rates reveal that a significant number of drug candidates fail in the later stage of clinical development owing to absorption, distribution, metabolism, elimination (ADME), and toxicity issues.
This book explores the most pertinent aspects and advancements in sonochemistry, dedicating nine chapters to fundamentals, synthesis methods, and applications.
The purpose of this handbook is to assist individuals for the Certified Pharmaceutical Good Manufacturing Practices Professional (CPGP) examination and provide a reference for the practitioner.
This book presents the papers included in the proceedings of the 7th International Conference of Reliable Information and Communication Technology 2023 (IRICT 2023) that was held in Pulai Springs Resorts, Johor, Malaysia on 27-28, December 2023.
This book provides a practical guide on the art and science of compassionate care in an era of healthcare crisis due to the COVID-19 pandemic that is inflicting long-lasting financial and psychosocial trauma on an unprecedented scale.
This book, now in a comprehensively revised and expanded third edition, covers the full spectrum of applications of Doppler ultrasound within Obstetrics and Gynecology.
The purpose of this ground-breaking Textbook is to describe and illustrate, with pedagogical features, the process by which social determinants of health (SDOH) has been integrated throughout all courses in the Nell Hodgson Woodruff School of Nursing.
Taxonomien sind Modelle, um unübersichtliche Domänen zu analysieren, Komplexität zu reduzieren sowie Unterschiede und Ähnlichkeiten von Objekten zu erkennen.
Leveraging Artificial Intelligence in Global Epidemics provides readers with a detailed technical description of the role Artificial Intelligence plays in various stages of a disease outbreak, using COVID-19 as a case study.
The Public Health Nursing: Scope and Standards of Practice, 3rd Edition, is an essential document for every public health nurse practicing in the United States.
The Public Health Nursing: Scope and Standards of Practice, 3rd Edition, is an essential document for every public health nurse practicing in the United States.
This fully updated new edition presents organic reaction mechanism questions, carefully selected from the primary chemical literature, to understand how reactants are transformed into products.
This book will give insight into emerging semiconductor devices from their applications in electronic circuits, which form the backbone of electronic equipment.
This book will give insight into emerging semiconductor devices from their applications in electronic circuits, which form the backbone of electronic equipment.
This book provides an introduction into the field of digital medicine, its wide spectrum of current clinical applications, and the future practice of medicine.
