Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the need to deliver a therapeutic vector to all muscles throughout the body.
The HLA molecules are important regulators of the immune response through mediating antigen presentation and interaction between key immune mediating cells.
This manual offers detailed protocols for fluorescence in situ hybridization (FISH) and comparative genomic hybridization approaches, which have been successfully used to study various aspects of genomic behavior and alterations.
Very Short Introductions: Brilliant, Sharp, Inspiring In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development.
This book provides a detailed overview of the latest developments in the rapidly evolving specialty of Neuro-Oncology arranged in approximately 500 questions arranged in multiple-choice and matching formats.
This book highlights recent research investigating psychological and neural mechanisms contributing to dysfunctional cognition in people with schizophrenia.
This volume explores and challenges the assumption that behavioral proclivities and pathologies are directly traceable to experience-an assumption that still widely dominates folk psychology as well as the perspective of many mental health practitioners.
This volume explores and challenges the assumption that behavioral proclivities and pathologies are directly traceable to experience-an assumption that still widely dominates folk psychology as well as the perspective of many mental health practitioners.
This book entitled "e;Cancer Stem Cell Markers and Related Network Path-ways"e; is about cancer stem cell (CSC) markers and the molecular network pathways.
Brain tumors comprise about 5-9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well.
Die Geschichte einer der mächtigsten und gefährlichsten Ideen der MenschheitMukherjee kreiert ein ambitioniertes und faszinierendes Panorama über den Versuch, das menschliche Genom zu entschlüsseln und in unser Erbgut einzugreifen.
This book explores the interrelationship of genetics, the environment, or both, in the causation of three neurodevelopmental disorders: autism/autism spectrum disorder (ASD), fetal alcohol spectrum disorder (FASD), and cerebral palsy (CP).
This innovative and engaging book argues that because our genetic information is directly linked to the genetic information of others, it is impossible to assert a 'right to privacy' in the same way that we can in other areas of life.
This innovative and engaging book argues that because our genetic information is directly linked to the genetic information of others, it is impossible to assert a 'right to privacy' in the same way that we can in other areas of life.
Very Short Introductions: Brilliant, Sharp, Inspiring In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development.
Strategies or decisions aimed at affecting, in a manner considered to be positive, the genetic heritage of a child in the context of human reproduction are increasingly being accepted in contemporary society.
The third edition of Craniofacial Embryogenetics and Development is dedicated to increased understanding of normal and abnormal orofacial development by integrating embryological development with its underlying genetic information.
From the Foreword by Candy Cooley, formerly Genetics Awareness Programme Lead at the NHS National Genetics and Genomics Education Centre: What a delight it is to read a book which takes complex scientific concepts and ensures they are understandable by all.
This book describes how obesity results from an imbalance between the intake of food energy and the expenditure of energy from physical activity and increases the risk of serious health problems including heart disease, stroke, osteoarthritis, and several types of cancer.
This book presents work that has been conducted as part of the research project "e;Discourse on ethical questions of biomedicine"e; of the interdisciplinary Working Group Bioethics and Science Communication at the Max-Delbrueck-Center for Molecular Medicine (MDC)in Berlin-Buch, Germany.
Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease.
This book reviews the recent research into biological aspects of suicide behavior and outlines each of the varied, recent approaches to prevent suicide.
In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses.
As our understanding of immune mediated chronic inflammatory diseases (IMIDs) grows, it becomes more and more clear that these conditions result from the convergence of a multitude of pathogenic mechanisms whose relative individual contribution is different in different patient subsets.
Employing accessible language throughout, this book covers the history of psychiatric research, the current state-of-the art in psychiatric practice, the physiological systems affected by psychiatric illnesses, the whole-body nature of these diseases and the impact that this aspect has on emerging biomarker discoveries.
This book reviews the current state of knowledge on the genetics, molecular biology and physiology of pendrin, with a particular focus on pendrin dysfunction and the consequences for human health.
This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome.
This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management.
The genotype/phenotype dichotomy is being slowly replaced by a more complex relationship whereby the majority of phenotypes arise from interactions between one's genotype and the environment in which one lives.
This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine.
This work was compiled to serve as a convenient source that covers a number of techniques (and details of their use) in the rather large field of nanomedicine, with special attention paid to gene delivery.
This book offers a comprehensive overview of the use of breast MRI for screening high-risk women, including those with familial-genetic hereditary predisposition and previous chest radiation therapy, typically lymphoma survivors.
