Medical genetics

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This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.

Early Life Origins of Health and Disease is a new book which presents and discusses the many factors that may have impact on normal development.

This book deals with the research and use of embryonic stem cells to combat a number of diseases and the legal limitations, arising mostly from bioethical concerns regarding human life.

Much research has focused on the basic cellular and molecular biological aspects of stem cells.

Rapid advances in pathogenetic insight, diagnostic and therapeutic modalities, and basic research continuously influence the state of the art in ophthalmology.

Two sigma receptor subtypes have been proposed, sigma1 and 2.

The book chapters cover different aspects of epilepsy genetics, starting with the "e;classical"e; concept of epilepsies as ion channel disorders.

Cystic Fibrosis has seen dramatic advances in treatment since the last edition, including targeted cystic fibrosis transmembrane conductance regulator (CFTR) protein modulators for most CFTR gene abnormalities.

Any professional concerned with immunology will be interested in this book dedicated to the memory of Milan Hasek, former director of the Prague Institute of Experimental Biology and Genetics.

A decade after the publication of The Man Behind the Syndrome, which was warmly received, particularly by medical geneticists, syndromologists and those doctors from many different dis- ciplines with an interest in medical history, Peter and Greta Beighton now present the second volume of their work, promised ten years ago.

This detailed volume explores the notable progress in the field of zinc finger proteins (ZFP) study through widely used methods and protocols involving their biological functions and applications.

In addition to the traditional cytogenetics still used as the basic methodology for everyday clinical diagnosis, new molecular cytogenetic techniques provide a useful basis for routine diagnosis.

About 7 million people worldwide are suffering from various inherited neuromuscular diseases.

This unique textbook provides a clear and concise overview of the key principles of the complex field of phylogenomics, with a particular focus on sequencing technologies that are crucial to studying and understanding interrelations in evolutionary genomics.

This book provides numerous methods for identification, validation, and functional characterization of chimeric RNAs, herein described as any transcript which contains the nucleotide sequence of two distinct parental genes.

Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior - First Prize winner of the 2013 BMA Medical Book Award for Basic and Clinical Sciences - explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes, which direct neurodevelopmental sequence.

The newest installment in this superb series presents descriptions of the latest DNA recombinants molecule technology.

This book summarizes microRNA (miRNA) biology in a variety of pathological processes, emphasizing the significant potential applications of miRNA in diagnostics and prognostics, as well as novel drug targets.

This special volume of Progress in Molecular Biology and Translational Science focuses on the genetics of stem cells.

The field of DNA repair is vast and advancing rapidly.

The title will develop from the 24th Stadler symposium.

A thorough introductory guide to the techniques of the musculoskeletal examinationSystematic Musculoskeletal Examinations is a clear, step-by-step learning text and atlas designed to teach essential and foundational skills of musculoskeletal physical assessment.

This volume is a compilation of sixteen chapters that detail reverse genetics protocols.

From the Foreword by Candy Cooley, formerly Genetics Awareness Programme Lead at the NHS National Genetics and Genomics Education Centre: What a delight it is to read a book which takes complex scientific concepts and ensures they are understandable by all.

This book offers a detailed overview of translational bioinformatics together with real-case applications.

Responding to the substantial growth that has taken place in the field over the past decade, this reference provides an in-depth overview of current thought on the genetics and genomics of asthma and COPD in relation to their pathogenesis and treatment.

Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry.

This volume details protocols for genetic, molecular, cytological, and bioinformatic methods for determining haplotypes.

This volume focuses on challenging field in biomedicine that is the genetic control of central immune tolerance.

Dieses Buch erläutert die neusten Technologien im Bereich Genmanipulation, Gentherapie und Klonierungen, insbesondere auch beim Menschen, die in den kommenden Jahren zunehmend in der Praxis eingesetzt werden könnten.

Carrier testing of adults provides information about the risk of passing a genetic mutation to your children, leading to reproductive (and some say, eugenic) decisions.

Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response provides the most comprehensive body of knowledge available on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients.

I am pleased to introduce this volume on Myoblast Transfer Therapy on behalf of the Muscular Dystrophy Association and all of its Advisory Committees.

This book highlights recent research investigating psychological and neural mechanisms contributing to dysfunctional cognition in people with schizophrenia.

This volume contains the proceedings of the meeting Genetics and Alzheimer's Disease held in Paris, on March 25,1988, by the Fondation Ipsen pour la Recherche Therapeuti- que.

The Human Genome Project was sold to the general public largely on the basis that a complete picture of the structure of human DNA would lead to new and better medicines.

Psychopathy: The Basics is an accessible text that provides a compact introduction to the major findings and debates concerning this complex personality disorder.

South America's Andean highlands have seen the rise and decline of several impressive, indigenous civilizations.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This text examines the relationship between DNA damage and repair, cellular senescence, genomic instability, and aging.

There is considerable interest in thermophile microorganisms, in their environments, their ability to survive at temperatures which normally denature proteins, but more importantly, as a valuable resource for bio- technology.

This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication.