Biochemistry

The volatile anesthetics continue to be one of the most mysterious yet commonly used class of drugs in medical practice today.

Perinatal problems in thyroid gland physiology are common but complicated and present a diagnostic dilemma for the primary clinician.

This volume addresses a fundamental puzzle in biology and medicine, namely, how does tissue develop, repair and replace itself.

This book contains selected proceedings from the NATO Advanced Study Institute (AS I) "e;The Molecular Pathology of Alcoholism"e; held at the Hotel Il Ciocco in Tuscany during 26th August - 6th September 1990.

This book has a dual purpose, to review in depth the control of fuel homeostasis in the brain and the role of the nervous system in the control of fuel deposition in the body.

Since the discovery of HIV-l as the etiologic agent of acquired immunodeficiency syndrome (AIDS) in the early 1980s, remarkable progress has been made in both the basic understanding of the biological processes leading to AIDS and an accelerated effort in finding new treatments.

The Streptomycetes are industrially widely used microorganisms due to their ability to produce numerous different chemical compounds.

It must be considered that there is nothing more difficult to carry out, nor more doubtful of success, nor more dangerous to handle, than to initiate a new order of things.

The Third International Symposium on Neurotransmitter Receptors was held in Hiroshima at a time when the entire field of neurotransmitter receptors in the brain is progressing at an unprecedented pace.

The past two decades have seen steady progress in our understanding of the pathogenesis of atherosclerosis.

The Fifth International Workshop on the Enzymology and Molecular Biology of Carbonyl Metabolism was held at Purdue University in June, 1990.

This volume contains a series of papers originally presented at the Symposium on Polymer Gels organized and sponsored by the Research Group on Polymer Gels,The Society of Polymer Science of Japan and co-sponsored by the Science and Technology Agency (ST A) and MIT!

The finding that chemicals can be metabolically activated to yield reactive chemical species capable of covalently binding to cellular macromolecules and the concept that these reactions could initiate toxicological and carcinogenic events stimulated a meeting by a small group of toxicologists at the University of Turku, in Finland, in 1975 (Jollow et al.

Elucidating the structures of biopolymers as they exist in nature has long been a goal of biochemists and biologists.

Present knowledge of the mechanisms underlying any single sensory modality is so massive as to discourage effort directed towards completeness.

The emergence of the Biochemical Sciences is underlined by the FAOB symposium in Seoul and highlighted by this Satellite meeting on the "e;New Bioenergetics.

Atherosclerosis is the principal underlying cause of cardiovascular and cerebrovascular disease in people of the Western world.

The elements in group 17 (VIlA) of the periodic table of elements-fluorine (F), chlorine (CI), bromine (Br), and iodine (I)-were designated by Berzelius as "e;halogens"e; (Greek hals, sea salt; gennao, I beget) because of their propensity to form salts.

This volume in the Advances in Experimental Medicine and Biology Series is dedicated to developing an overall view of the "e;state-of- the-art"e; of knowledge in the field of phospholipase A2 and to exploring the role and function of this enzyme in various inflammatory diseases.

This is the proceedings of the fourth in a series of inter- national gatherings on kindling held on the University of British Columbia campus, June 15-17, 1989.

It has been acknowledged that the physiological effects of dietary fiber are an exceedingly complex matter which requires a multidisciplinary research effort.

There is a prov1s10n in the charter of each Study Section of the Division of Research Grants at the National Institutes of Health that stipulates that "e;workshops"e; are to be held periodically to aid Study Section members in their appraisals of recent developments in their fields and to identify future challenges worthy of investigation.

The present volume originated from the workshop "e;Transduction in Biological Sys- tems,"e; held at the Marine Biological Station of the Universidad de Valparaiso, Mon- temar, Chile, May 23-30, 1988, and contains contributions from most of the partici- pants in the workshop.

Twenty years ago, the enzyme superoxide dismutase which uses the superoxide radical anion as its specific substrate was reported.

This book is the story of the marriage of a new techl}ology, computers, with an old problem, the study of neuroanatomical structures using the light microscope.

The Sixth International Symposium on Calcium-Binding Proteins in Health and Disease was held in Nagoya, Japan, July 24-28, 1988.

These two volumes contain articles presented at the Vlth International Symposium on Human Purine and Pyrimidine Metabolism held in Hakone, Japan ,July 17 trough 21, 1988.

The use of aqueous two-phase systems for the partitioning of macromolecules, organelles and cells was originally developed by Per-Ake Albertsson in Sweden in the mid-fifties [1-3].

The Ottawa '88 meeting of the International Society for Oxygen Transport to Tissue attracted a record number of participants and presentations.

This book contains the scientific contributions presented at an International Symposium held in Sorrento, Italy, in June 1988 under the auspices of the University of Naples, the Italian Society of Biochemistry, and the National Research Council.

This volume is based on an international symposium held during September 9-12, 1986 in Bocca di Magra, Italy.

A widespread appreciation for the role that calcium plays in cell physiology and patho- physiology has now been achieved due to the pioneering studies of many of the scientists who attended the VIIth International Spring Symposium on Health Sciences at George Washington University in Washington, D.

This book is based on the papers presented at the "e;Fourth International Congress on Oxygen Radicals (4-ICOR),"e; held June 27 - July 3, 1987, at the University of California, La Jolla.

When phagocytes are exposed to a number of different stimuli, they undergo dra- matic changes in the way they process oxygen.

The characterization of the cellular and molecular mechanisms that mediate inflammation provides a foundation that supports future studies that will de- fine mechanisms more intimately.

The basis of all immunoassays is the interaction of antibodies with antigens.

This volume contains the proceedings of the International Conference on Prostaglandins and Lipid Metabolism in Radiation Injury held in Rockville, Maryland, on October 2-3, 1986.

This volume contains the texts of the nineteen lectures presented at the NATO-ASI - FEBS Course on "e;DNA - ligand interactions: from drugs to proteins.

The present book might be regarded as a sequel to my previous work, Bioinorganic Chemistry: An Introduction (Allyn and Bacon, 1977).

This volume collects a number of the invited lectures and a few selected contrib- utions presented at the International Symposium on Structure and Dynamics of Nucleic Acids, Proteins and Membranes held August 31st through September 5th, 1986, in Riva del Garda, Italy.

The Sixth Annual International Spring Symposium on Health Sciences, held in Washington, D.

Platelet-activating factor (PAF) is the commonly used name for a group of potent biologically active, ether-linked phospholipids, the alkylacetylglycerophospho- cholines.