Biochemistry

Seventeen years after the 2nd International Symposium on Oxygen Transport to Tissue, which was held in Mainz in March 1975, the local Organizing Committee and the Board of ISOTT were pleased to host the ISOTT Conference in Mainz on the Rhine again.

Alcohol abuse and alcoholism are international problems whose costs economical- ly, psychologically and medically have been well documented.

This compendium is the result of the FEMS Workshop on "e;Rapid Diagnosis of Mycoplasmas"e; which I organized and which took place in Jerusalem, Israel, August 11-23, 1991.

It is now well recognised that the texture of foods is an important factor when consumers select particular foods.

by G.

These volumes record the presentations made at the VIII International Symposium on Purine and Pyrimidine Metabolism in Manheld at Indiana University, Bloomington, USA from May 22- May 27, 1994.

Progress in Cell Cycle Research is a new annual series designed to be the source for up-to-date research on this rapidly expanding field.

There is considerable interest in thermophile microorganisms, in their environments, their ability to survive at temperatures which normally denature proteins, but more importantly, as a valuable resource for bio- technology.

An International Syaposiua on Free Radicals in Diagnostic Medicine was co-sponsored by the state University of New York at Buffalo, Roswell Park Cancer Institute, and the Upstate NY Section of the American Association of Clinical Chemistry.

The Human Genome Project, an endeavor to map and sequence the entire human genome, has been in existence for almost seven years.

The first International Symposium on Urolithiasis Research was held in Leeds, England, in 1968.

The 4th International Conference on Hemochromatosis and the 11th International Conference on Iron and Iron Proteins took place in Jerusalem on April 27 -30 and on May 2 -7 1993, respectively.

Lactoferrin is an intriguing protein with an interesting structure and several known or suggested biological activities.

This is the first volume to provide comprehensive coverage of acetogenesis.

During the past decade, the study of the chemical structures used by insects has advanced from a subject that could be reviewed in a single volume to a vastly more advanced level.

CK2 is a protein serine/threonine kinase which is a highly conserved and ubiquitous protein kinase.

It is an authentic privilege to have the opportunity to assemble and edit a new volume on "e;Prolactin,"e; the first in several decades to be devoted to this fascinating hormone in all its aspects.

The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data.

As discussed in this book, a large body of evidence indicates that selenium is a cancer chemopreventive agent.

The localized attachment of circulating leukocytes to endothelium has been recognized as the cellular hallmark of the inflammatory response.

Profound mortality rates, due to cardiovascular disease, are a worldwide problem.

Dr.

An understanding of the mechanisms by which plants perceive environmental cues, both physical and chemical, and transduce the signals that influence specific expression of genes, is an area of intensive scientific research.

This volume represents a collection of lectures delivered by outstanding specialists in the fields of biophysics and of related scientific disciplines th during the 7 International Summer School on Biophysics held in Rovinj, Croatia from 14 to 25 September 2000 under the title "e;Super molecular Structure and Function "e;.

Since 1984, we have organized satellite symposia on retinal degenerations that are held in conjunction with the biennial International Congress of Eye Research.

Scientists from many disciplines require making observations which are dependent upon the behavior of compounds in solution.

During the last two decades, chemical and cellular studies have contributed enormously to our understanding of metal-induced carcinogenesis, and many hypotheses on the role of metals in pathophysiological processes have been investigated.

This is the second edition of the text "e;Bioreaction Engineering Principles"e; by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer).

This volume is divided into three sections.

Genetic Engineering, Volume 24 contains discussions of contemporary and relevant topics in genetics, including: -Gene silencing: principles and applications, -Integrins and the myocardium, -Plant virus gene vectors: biotechnology and applications in agriculture and medicine, -Novel approaches to controlling transcription, -Use of DNA polymorphisms in genetic mapping, -Application of FLP/FRT site-specific DNA recombination system in plants.

Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control.

A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes.

This volume represents the proceedings of the 9th International Proton Transport Conference, "e;Mechanisms and Consequences of Proton Transport"e; held in Leura, Australia, August 19 -21, 200 I.

Pteridine and folate research has long been recognized as important for many biological processes, such as amino acid metabolism, nucleic acid synthesis, neurotransmitter synthesis, cancer, cardiovascular function, and growth and development of essentially all living organisms.

From somewhat enigmatic beginnings 40 years ago, guanylate cyclase research has emerged to occupy a position of prominence in the study of signal transduction.

Microarray technology is a major experimental tool for functional genomic explorations, and will continue to be a major tool throughout this decade and beyond.

This book was stimulated by the enthusiasm shown by attendees at the meetings in Saxon River, VT, sponsored by the Federation ofAmerican Societies for Experimental Biology (FASEB), on the subject of the intestinal processing of lipids.

Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases.

Potassium channels (K+) are membrane-spanning proteins which serve many important functions and are becoming a hot topic in physiology.

Biophysical studies in the 1950ies and 1960ies led to the realization that the water permeability of certain biological membranes must be due to the presence of water transporting proteins.

Since the late 1960s, there has been an acceleration of research focused on understanding how the efferent ducts, the epididymis, and the vas deferens function with respect to the maturation and storage of spermatozoa and as hormone dependent tissues.

It is generally accepted that the recent progress in molecular and cellular biology would not have been possible without an understanding of the mechanisms and signaling pathways of communication inside the cell and between various cells of the animal organism.

One of the most significant challenges facing mankind in the twenty-first century is the development of a sustainable global economy.

This series of books, which is published at the rate of about one per year, addresses fundamental problems in materials science.

The Boron '97 meeting was a great success in summarising all recent developments in basic and applied research on boron's function, especially in plants.

PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man.

Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions.