Biochemical Modulation at the present time defines an area of study in which the intracellular metabolism of a given anti- cancer agent is modulated (usually by a noncytotoxic agent or a cytotoxic agent at sufficiently low dosage to make it non- cytotoxic) in order to either increase the effectiveness of the particular agent against tumor cells or decrease its cytotox- icity against normal cells.
The success rate for treatment of primary neoplasms has improved sig- nificantly due to improved surgical, radiotherapy, and chemotherapy methods, and by supportive patient care.
As stated by Buckminster Fuller in Operation Manual for Spaceship Earth, "e;Synergy is the behavior of whole systems unpredicted by separately observed behaviors of any of the system's separate parts"e;.
This volume surveys the current status of many of the important methods and approaches which are central to the study of protein structure and function.
With the power and range of modern pulse spectrometers the compass of NMR spec- troscopy is now very large for a single book-but we have undertaken this.
During the past three decades, the sugar moiety of complex carbohydrates has been found to be involved in important interactions of immunological specificity of antigens and to participate in a variety of cellular functions.
The prediction of the conformation of proteins has developed from an intellectual exercise into a serious practical endeavor that has great promise to yield new stable enzymes, products of pharmacological significance, and catalysts of great potential.
This volume is based in part upon the proceedings of the Calcium Theme held during the 67th Annual Meeting of the Federation of American Societies for Experimental Biology, which took place in Chicago, AprillO-lS, 1983.
In the first edition of The Enzymes of Biological Membranes, published in four volumes in 1976, we collected the mass of widely scattered information on membrane-linked enzymes and metabolic processes up to about 1975.
This text is a summary of basic principles and techniques and is dedicated to all those students who have been told by their mentors, "e;Go forth and do two-dimensional gels and have the results on my desk tomorrow.
This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews dedi- cated, on the occasion of the 40th anniversary of the inauguration of the Heart Research Group in Berlin-Buch that today forms a part there of the Max Delbriick Center for Molecular Medicine, to Professor Albert Wollenberger, founder of the Heart Research Group and for 21 years its head.
The chapters in this volume are the Proceedings of the Satellite Symposium of the XVIth World Congress of the International Society for Heart Research on `Signal Transduction in Normal and Diseased Myocardium' which was held in Rotterdam at the Faculty of Medicine & Health Sciences of the Erasmus University, June 30 and July 1, 1995.
This volume presents the proceedings of the Fourth Annual Symposium on the Molecular Biology of Hemopoiesis, held in Reno, Nevada, November 1 and 2, 1988.
The belief that energy might be a limiting factor for the development of humanity led twenty years ago to a great interest being'taken in research on anaerobic digestion.
Volume 8 of Advances in Nutritional Research deals with several topics of prime current interest in nutritional research, including the role of nutrition in hypertension, in the infections associated with protein-energy malnu- trition, and in pathological conditions associated with the generation of oxygen radicals in the tissues, as well as with topics of ongoing interest.
If ripple effect is a measure of greatness in scientific discovery then GEMMOs have a lot going for them and this book dramatically illustrates the risks associated with advances being made by researchers to mobilize and control the power of the microorganism in the world's fight to perfect nature and fmd remedies for its imperfections.
This monograph consists of manuscripts, summary statements, and poster abstracts submitted by invited speakers and poster contributors who participated in the symposium "e;Oxygen Complexes and Oxygen Activation by Transition Metals,"e; held March 23-26, 1987, at Texas A&M University.
This book contains the lectures of the second course devoted to bioelectro- chemistry, held within the framework of the International School of Biophysics.
This book was originated from a series of lectures given in a course on the physical properties of biological membranes and their functional implica- tions.
In the mid-1960's, scientists working on carotenoids throughout the World agreed to have periodic meetings for the purpose of discussing and disseminating scientific research results concerning all aspects of carotenoids.
I organized this book because there is a need to put together in book form recent advances in our knowledge of how airway smooth muscle:works in health and in disease.
The diversity of the chapters presented in this volume illustrates not only the many applications of lasers, but also the fact that, in many cases, these are not new uses of lasers, but rather improvements of laser techniques already widely accepted in both research and clinical situations.
Plasma lipoproteins constitute a unique macromolecular system of lipid-protein complexes responsible for the transport of lipids from their sites of origin to their sites of utilization either as metabolic fuel or as structural components of cell membranes.
The World Congress of In Vitro Fertilization and Alternate Assisted Reproduction, held in Jerusalem, Israel, 2-7 April, 1989, was the sixth in the sequence of these Congresses, but was the first to emphasize the major importance and the place of assisted reproductive technologies in the treatment of infertility.
