Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival.
The Golgi Apparatus: The First 100 Years traces the first 100 years of Golgi apparatus discovery from the first published accounts from Pavia, Italy in 1898 to the Centenary Celebration in Pavia, Italy in 1998 and into the decade beyond.
This second edition volume is a companion volume to the previous edition and looks at new findings on novel bioactive chemicals and cognate targets, as well as the use of synthetic small molecules and a variety of tools to understand these processes.
Written by nearly 60 of the world's leading investigators in this rapidly expanding field, this state-of-the-art reference furnishes detailed presentations on the basic science and clinical aspects of cilia, mucus, and mucociliary interactions.
The anther tapetum, present in all land plants, is a highly specialized, transient tissue surrounding the (micro-)spores and/or pollen grains during their development.
Data Analysis in Molecular Biology and Evolution introduces biologists to DAMBE, a proprietary, user-friendly computer program for molecular data analysis.
Offering a wide array of illustrations and tables in every chapter, this book extensively covers the principles of allosterism in reference to drug action and progresses to a detailed examination of individual ionotropic and G-protein coupled receptor systems-helping those new to the subject understand the importance of allosterism and providing th
This book offers a comprehensive perspective of herbal medicine phytochemistry and explores the application of plant extracts as bioactive compounds in disease prevention and treatment in modern or traditional medicine.
Estuaries in every country exemplify the same paradox- they are among the most productive ecosystems and also among the most impacted by anthropogenic activities.
Secretory Proteins, Volume 133 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, including chapters on Proprotein Convertases regulate trafficking and maturation of key proteins within the secretory pathway, Secretory Proteins in Cancer Diagnosis, Senescent Cells and SASP in Cancer Microenvironment: new approaches in cancer therapy, Autophagy for secretory protein: Therapeutic targets in cancer, Secretory proteins and pathways of secretion of osteosarcoma, Monocyte secretory proteins as drug targets for arresting progression of atherosclerosis, The secretory phenotypes of envenomed cells: insights into venom cytotoxicity, Macromolecules for secretory pathway in SARS-CoV-2 infection, and much more.
The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists.
Epigenetics in Health and Disease, Volume 198 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-dCas9 Systems for Epigenetic Editing for Therapeutic Applications, Epigenetics in heredity disease, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Histone deacetylase (HDACs) Inhibitors: Clinical applications, Early epigenetic markers for precision medicine, Epigenetics of neurological diseases, Epigenetic Regulons in Alzheimer's disease, and Epigenetics in epilepsy.
Several books on the market cover combinatorial techniques, but they offer just a limited perspective of the field, focusing on selected aspects without examining all approaches and integrated technologies.
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes.
Developed from the efforts of a multiyear, international project examining how persistent, bioaccumulative, and toxic (PBT) chemicals are evaluated and managed, Persistent, Bioaccumulative, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices focuses on improving the processes that govern PBTs.
Protein Biosynthesis Interference in Disease offers a thorough discussion and overview of protein biosynthesis interference, its mechanisms of action, and influence over disease processes.
The rapid development of efficient computational tools has allowed researchers to tackle biological problems and to predict, analyse and monitor, at an atomic level, molecular recognition processes.
A Special Publication of the Society of Environmental Toxicology and Chemistry (SETAC)Aquatic Mesocosm Studies in Ecological Risk Assessment discusses the methods currently used for conducting simulated field studies and provides a series of case histories in which mesocosm type studies have been used to assess the impact of pesticides on aquatic ecosystems.
International concern in scientific, industrial, and governmental communi- ties over traces of xenobiotics in foods and in both abiotic and biotic envi- ronments has justified the present triumvirate of specialized publications in and this field: comprehensive reviews, rapidly published research papers progress reports, and archival documentations.
Volume 25, entitled Modern Avenues in Metal-Nucleic Acid Chemistry, of the series Metal Ions in Life Sciences (MILS), provides a timely overview of selected relevant developments in a field which previously had a pronounced focus on fundamental chemistry aspects such as coordination principles, structural chemistry, and consequences for biological processes and disease-related medicinal issues.
Nanoparticles can be synthesised via a number of methods, including chemical vapor deposition, ball milling, laser ablation, thermal decomposition and chemical reduction.
Since the popular second edition of The Laboratory Swine was published more than a decade ago, the number of pigs used in toxicity studies has increased as an alternative to commonly used non-rodent species, while, at the same time, large developments have been made in welfare concepts of laboratory animals.
Biochemical Pathways and Environmental Responses in Plants, Part A, Volume 676 in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on topics such as Structure, function, and engineering of plant polyketide synthases, A sensitive LC-MS/MS assay for enzymatic characterization of methylthioalkylmalate synthase involved in glucosinolate side-chain elongation, Assaying formate-tetrahydrofolate ligase with monoglutamylated and polyglutamylated substrates using a fluorescence-HPLC based assay, An Approach to Nearest Neighbor Analysis of Pigmented Protein Complexes by Using Chemical Crosslinking in Combination with Mass Spectrometry, and much more.
Carrier-bound Immobilized Enzymes The first systematic overview of this key technique since the early 1990s, this authoritative reference is the only handbook available to include all recent developments.
In life science, bioluminescence and chemiluminescence have become a vital tool for laboratory analysis and biomedical imaging both in academic research and industrial product development.
Sets the stage for the development of better diagnostic techniques and therapeutics Featuring contributions from an international team of leading clinicians and biomedical researchers, Molecular Basis of Oxidative Stress reviews the molecular and chemical bases of oxidative stress, describing how oxidative stress can lead to the development of cancer and cardiovascular and neurodegenerative diseases.
This first book to cover this new topic at the interface of cell biology, immunology and infection biology offers a unique insight as to how the innate and possibly the adaptive immune system are shaped by cellular mechanisms.