This first book to cover this new topic at the interface of cell biology, immunology and infection biology offers a unique insight as to how the innate and possibly the adaptive immune system are shaped by cellular mechanisms.
Marine environment can be affected by several pollutants such as the presence of elements and their chemical species, pharmaceuticals, nanoparticles and other emerging contaminants.
Chemical substances, physical agents and built structures exhibit various types of hazard due to their inherent toxic, mutagenic, carcinogenic, reprotoxic and sensitizing character or damaging to the immune and hormone system.
Peroxynitrite is a powerful oxidiser which can damage a wide array of molecules within cells, including DNA and proteins, leading to apoptosis, inflammation or cancer.
Fish Physiology: Organic Chemical Toxicology of Fishes discusses the different types of organic chemical contaminants and their respective toxic effects in fish.
During the fifteen years since the bestselling first edition of Folate in Health and Disease was published, there have been thousands of new research studies related to folate and its role in health and disease.
Chemistry and Technology of Plant Substances: Chemical and Biochemical Aspects demonstrates the progress and promise of developing new chemical substances from renewable sources of chemical raw materials.
Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations.
Predictive data science is already in use in many fields, but its application in toxicology is new and sought after by non-animal alternative testing initiatives.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.
Non-communicable diseases, such as cardiovascular disease, cancer, diabetes, obesity, and hypertension, represent the cause of 60% of all deaths around the globe.
This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy.
The 30th scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) was held at the Western Conference Centre, UMIST, Manchester, in August 2002.
This book, which has been prepared by an international group of experts, provides comprehensive guidance for the design, planning and implementation of assessments and monitoring programmes for water bodies used for recreation.
Advances in Microbial Physiology, Volume 75, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology.
This reference work provides a comprehensive review of cell and tissue differentiation and its role in the formation of specific secondary metabolites.
This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein-protein interactions in the human adenovirus capsid, to mention but a few.
This book provides detailed and comprehensive information on oxidative damage caused by stresses in plants with especial reference to the metabolism of reactive oxygen species (ROS).
Edited by one of the leading experts in the field, this book fills the need for a book presenting the most important methods for high-throughput screenings and functional characterization of enzymes.
This eclectic volume features two major topics: applications of mass spectrometry in bioscience; and computational methods for analysis of protein structure and interactions with other macromolecules.
This series provides inorganic chemists and materials scientists with a forum for critical, authoritative evaluations of advances in every area of the discipline.
Tolerance, the ability of populations to cope with the chemical stress resulting from toxic contaminants, has been described in many organisms from bacteria to fungi, from phytoplankton to terrestrial flowering plants, and from invertebrates such as worms to vertebrates like fish and amphibians.
This volume is the third of a series on Membrane Proteins and, like the pre- ceding manuals, is the result of an International Advanced Course entitled Isolation and Characterization of Membrane Proteins: Biochemical and Bio- physical Aspects sponsored by the Federation of European Biochemical So- cieties (FEBS) and the Italian Research Council (CNR).
Methods of proteomics have been shown to be powerful tools in search of target proteins - proteins that respond in cells to an internal or an external stimulus.
Computational Approaches for Studying Enzyme Mechanism Part A, is the first of two volumes in the Methods in Enzymology series, focusses on computational approaches for studying enzyme mechanism.
In anschaulicher Form – unterstützt durch zahlreiche Abbildungen – wird in diesem aktualisierten Lehrbuch in die Methode der Kristallstrukturbestimmung eingeführt.
