This is the first book to collect and summarize in one publication the efforts to use kinases or phosphatases for drug development against parasite infections.
This book illustrates experimental and computational methodologies used to achieve cost effective biological processes for the production of fuels and biochemicals through multiple approaches to increasing yield, titers, and productivity in a robust host.
This timely resource offers extensive discussions on the pharmacological, environmental,endocrinological, and natural factors that alter reproductive or developmental processes-elucidating the effects of toxicants on mechanisms of reproduction.
Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species.
Building on the success of the 14 previous editions, this remarkable reference has been extensively reorganized and expanded and now comprises almost 1,500 individual drug articles providing the most complete coverage of adverse reactions and interactions found anywhere.
Endosomes are a heterogeneous population of endocytic vesicles and tubules that have captivated the interest of biologists for many years, partly due to their important cellular functions and partly due to their intriguing nature and dynamics.
In response to the field's need for an introductory text, the authors have distilled the vast and scattered literature relating to the biotechnology of microbial secondary metabolites.
Vector-borne infectious diseases, such as malaria, dengue fever, yellow fever, and plague, cause a significant fraction of the global infectious disease burden; indeed, nearly half of the world's population is infected with at least one type of vector-borne pathogen (CIESIN, 2007; WHO, 2004a).
Produced by a Leading Aquatic ScientistA narrative account of how estuaries around the world are being altered by human forces and human-induced global climate changes, Climate Change and Coastal Ecosystems: Long-Term Effects of Climate and Nutrient Loading on Trophic Organization chronicles a more than 40-year-old research effort conducted by Dr.
The authors describe basic theoretical concepts of vibrational spectroscopy, address instrumental aspects and experimental procedures, and discuss experimental and theoretical methods for interpreting vibrational spectra.
The study of endotoxins has undergone cycles of enthusiastic research followed by neglect and revival again due to newly described biological effects attributed to endotoxins.
Since photosynthetic performance is a fundamental determinant of yield in the vast majority of crops, an understanding of the factors limiting photosynthetic productivity has a crucial role to play in crop improvement programmes.
Taking an interdisciplinary approach that emphasizes the adaptability of immunochemical and related bioanalytical methods to a variety of matrices, Immunoassay and Other Bioanalytical Techniques describes the strength and the versatility of these methods in a wide range of environmental and biological measurement applications.
This monograph brings together the proceedings of a workshop held in Geneva, Switzerland in March 2000 under the joint sponsorship of the University of Sheffield and F Hoffmann La Roche Ltd.
Advances in Enzymology and Related Areas of Molecular Biology is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology.
Membrane proteins continue to be prime drug targets because they perform essential processes in the cell including controlling the flow of information and materials between cells and mediating activities like hormone action and nerve impulses.
This book delves into the vital role of plants and their bioactive compounds in human health, emphasizing their medicinal and nutritional significance.
This volume explores strategies and detailed protocols for the preparation of macromolecular complexes and their characterization in view of structural analysis.
Photoaging results from chronic exposure to UV radiation and is an increasingly common clinical feature, with an aging population the clinical burden is likely to increase despite advances in our understanding of the pathology and development of improved treatments.
Simplistic thinking would have us believe that by eliminating the loading of a given pollutant, an aquatic system will revert to its previous pristine state.
A UN report presented to the UN Human Rights Council in 2017 recognized that, "e;although pesticide use has been correlated with a rise in food production, it has had catastrophic impacts"e; on human health and the environment.
Methods of Enzymatic Analysis, Volume 4 reviews developments in the use of enzymes as tools in analytical biochemistry, including advances in assay techniques.
Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches.
Basic Environmental Toxicology provides a thorough, systematic introduction to environmental toxicology and addresses many of the effects of pollutants on humans, animals, and the environment.
Thirty carefully selected, peer-reviewed contributions from the International Conference on Pure and Applied Chemistry (ICPAC 2016) are featured in this edited book of proceedings.
Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide.
Many biologists and ecologists have developed models that find widespread use in theoretical investigations and in applications to organism behavior, disease control, population and metapopulation theory, ecosystem dynamics, and environmental management.
Computational Molecular modelling in Structural Biology, Volume 113, the latest release in the Advances in Protein Chemistry and Structural Biology, highlights new advances in the field, with this new volume presenting interesting chapters on charting the Bromodomain BRD4: Towards the Identification of Novel Inhibitors with Molecular Similarity and Receptor Mapping, and Computational Methods to Discover Compounds for the Treatment of Chagas Disease.
Toxicity of Nanoparticles in Plants: An Evaluation of Cyto/Morpho-physiological, Biochemical and Molecular Responses, Volume Five in the Nanomaterial-Plant Interactions series, reviews the latest research on toxicological effects of using nanotechnology in plants.
Phytoremediation, Volume 83, the latest release in the Advances in Botanical Research series, covers a variety of new topics, including Metallophytes from calamine and serpentine soils (incl.
This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells.
The book is divided into four parts: the first part introduces the basic concepts of nicotinamide coenzymes, the synthesis of nicotinamide coenzymes, intracellular distribution, and an overview of the main functions and detection methods so that readers can quickly understand the general feature and function of nicotinamide coenzymes; the second part describes the involvement of nicotinamide coenzymes in intracellular signal transduction and their roles in cellular physiological and biochemical processes to explain exactly how nicotinamide coenzymes work in the processes and enable readers to deeply understand the principle of nicotinamide coenzymes playing an important function; the third part describes the role of nicotinamide coenzymes in the pathophysiological process of diseases, tries to illustrate the specific mechanisms of their association with the occurrence of the diseases, and points out the potential value in future translational medicine research; the fourth part introduces the production technology of nicotinamide coenzymes, including precursors, the process of industrial production, and the application of nicotinamide coenzymes and precursors in health industry, medicine, and life science research.
Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health.
Nanoarmoring of Enzymes: Rational Design of Polymer-Wrapped Enzymes, Volume 590 is the latest volume in the Methods in Enzymology series that focuses on nanoarmoring of enzymes and the rational design of polymer-wrapped enzymes.
