This volume is aimed at explaining how drug repurposing works; to what extent the initial hopes have been realised in finding drugs for neurodegenerative diseases, psychiatric disorders, cancer and diseases caused by parasitic worms.
This volume is aimed at explaining how drug repurposing works; to what extent the initial hopes have been realised in finding drugs for neurodegenerative diseases, psychiatric disorders, cancer and diseases caused by parasitic worms.
Building on key reactions presented in Volume 1, Synthetic Methods in Drug Discovery Volume 2 covers a range of important reaction types including organometallic chemistry, fluorination approaches and asymmetric methods as well as new and exciting areas such as Csp2-Csp3 couplings, catalytic amide bond forming reactions, hydrogen borrowing chemistry and methods to access novel motifs and monomers.
Epigenetics is one of the fastest moving fields in drug discovery, with almost every large pharmaceutical company and a substantial number of biotechnology companies targeting epigenetic processes to treat diseases ranging from cancer to Huntington's disease and from inflammation to sickle cell anaemia.
Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents.
This unique book describes the latest information in the fundamental understanding of the biophysics and biochemistry of articular cartilage using the state-of-the-art practices in NMR and MRI.
Synthetic biology is a new area of biological research that combines science and engineering in order to design and build novel biological functions and systems.
This book explores the potential of microbial metabolism in health, agriculture, and environmental technologies, serving as a comprehensive guide to microbial metabolomics with practical applications.
Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents.
There has been enormous progress in our understanding of molybdenum and tungsten enzymes and relevant inorganic complexes of molybdenum and tungsten over the past twenty years.
In many fields, most notably medicine and molecular biology, the understanding of the structure and function of carbohydrates and glycoconjugates remains vital.
The third edition features a re-organization into multiple sections including: Mycotoxin Contamination in Feedstuffs for Farm Animals; Mycotoxin Contamination in Feedstuffs for Pets; Further Mycotoxins and Microbial Metabolites in Feedstuffs; Tables of Mycotoxins in Feedstuffs; Feedstuffs for Farm Animals and their Mycotoxins; Feedstuffs for Pets and their Mycotoxins; Mycotoxin Contamination of Feedstuffs in Conventional and Organic Farming; and Geographical Occurrence of Mycotoxins in Feedstuffs.
The third edition features a re-organization into multiple sections including: Mycotoxin Contamination in Feedstuffs for Farm Animals; Mycotoxin Contamination in Feedstuffs for Pets; Further Mycotoxins and Microbial Metabolites in Feedstuffs; Tables of Mycotoxins in Feedstuffs; Feedstuffs for Farm Animals and their Mycotoxins; Feedstuffs for Pets and their Mycotoxins; Mycotoxin Contamination of Feedstuffs in Conventional and Organic Farming; and Geographical Occurrence of Mycotoxins in Feedstuffs.
There has been enormous progress in our understanding of molybdenum and tungsten enzymes and relevant inorganic complexes of molybdenum and tungsten over the past twenty years.
This book links oxygen metabolism from experimental animal models to human clinical applications, bringing together concepts and knowledge from laboratory models to clinical practice.
The simulation of enzymatic processes is a well-established field within computational chemistry, as demonstrated by the 2013 Nobel Prize in Chemistry.
This book links oxygen metabolism from experimental animal models to human clinical applications, bringing together concepts and knowledge from laboratory models to clinical practice.
Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation.
The incorporation of Green Chemistry is a relatively new phenomenon in the drug discovery discipline, since the scale that chemists operate on in drug discovery is smaller than those of process and manufacturing chemistry.
In recent years there has been increasing evidence of the importance of carbohydrates and glycoconjugates in biomedical applications, and the use of synthetic ligands based on carbohydrates as drugs has received much attention.
Synthetic receptor molecules, molecules that mimic antibody recognition, are widely used for developing drug leads; drug delivery vehicles; imaging agents; sensing agents; capture agents and separation systems.
This book provides a history and discussion of the use of human tissues as an alternative to animal-based testing for assessing the efficacy and safety of new medicines.
This contributed volume on phytochemistry and pharmacology of the genus Bidens covers the chemical constituents and biological activities of this plant group in detail.
This book comprehensively reviews the interplay between hormones and biofilms, uncovering the complex ways in which hormonal signals impact microbial communities and the formation of biofilms.
This book comprehensively reviews the interplay between hormones and biofilms, uncovering the complex ways in which hormonal signals impact microbial communities and the formation of biofilms.
