In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future.
This book critically discusses different aspects of algal production systems and several of the drawbacks related to microalgal biomass production, namely, low biomass yield, and energy-consuming harvesting, dewatering, drying and extraction processes.
Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis.
Die derzeitige rasche Entwicklung in der Medizin und Mikrobiologie erfordert zwingend, ein konzeptionell neues Lexikon der Infektionskrankheiten des Menschen herauszugeben.
Bioconjugate Techniques is the essential guide to the modification and crosslinking of biomolecules for use in research, diagnostics, and therapeutics.
Enzymology at the Membrane Interface, the latest volume in the Methods in Enzymology series, covers a subset of enzymes that work in the environment of the biological cell membrane.
This book was developed from the papers presented at a symposium on "e;Water Relationships in Foods,"e; which was held from April 10-14, 1989 at the 197th National Meeting of the American Chemical Society in Dallas, Texas, under the auspices of the Agricultural and Food Chemistry Division of ACS.
Today, we are exposed to an increasing number of chemicals in the environment and there is a growing awareness of the effects of these chemicals on the ovaries.
This volume provides readers with a broad collection of theoretical, computational, and experimental methods to quantitatively study the properties of phase-separate biomolecular condensates in diverse systems.
The cell can be viewed as a 'collection of protein machines' and understanding these molecular machines requires sophisticated cooperation between cell biologists, geneticists, enzymologists, crystallographers, chemists and physicists.
The clinical approaches to the chronic degenerative diseases that drain our resources, and compromise our well-being, have become almost exclusively symptom-focused.
Enzyme Regulation in Metabolic Pathways shows the reader how to understand the roles of enzymes and their kinetic constants in intermediary metabolism.
Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists.
For some 50 years, Professor Asakawa and his group have focused their research on the chemical constituents of bryophytes and have found that these plants contain large numbers of secondary metabolites, such as terpenoids, acetogenins, and aromatic compounds representative of many new skeletons, which exhibit interesting biological activities.
Despite the historical signifigance of flavonoids and their pigments in establishing the basis for modern genetics, research in this large group of secondary metabolites continues to be more intense than ever.
This edited book provides knowledge about hemicelluloses biorefinery approaching production life cycle, circular economy, and valorization by obtaining value-added bioproducts and bioenergy.
Known worldwide as the standard introductory text to this important and exciting area of study, Gene Cloning and DNA Analysis: An Introduction, 8th Edition preserves the tradition of excellence created by previous editions.
Translational mitochondrial medicine applies the knowledge of experimental medicine in clinical practice, it is a prospective direction of the development of mitochondrial medicine.
While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing analytical technology that has permitted us entry into the genomic era and a whole new level of scientific understanding.
Whole-cell biocatalysis is a promising and emerging field of biological science that is mostly based on advancements in biosystems engineering for the production of useful products such as chemicals, fuels, and pharmaceuticals.
In this book, the effect of nutritional habits and wine consumption on ageing and the main degenerative diseases (cardiovascular, cancer, Alzheimer's, etc.
Recent Advances in Phytochemistry, Volume 5: Structural and Functional Aspects of Phytochemistry covers the proceedings of the 10th Symposium of the Phytochemical Society of North America held in Beltsville College Park, Maryland on October 6-9, 1970.
Updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods, Fifth Edition supplies new chapters on topics currently impacting the field including cutaneous metabolism, skin contamination, exposure to protein allergens, in vitro absorption methodology and the percutaneous absorption of chemical mixtures.
Methane and its oxidation product, methanol, have occupied an important position in the chemical industry for many years: the former as a feedstock, the latter as a primary chemical from which many products are produced.
New data continually indicate that antioxidants may contribute to reductions in cancer risks and that chronic consumption of low levels of chemical carcinogens in our diet may contribute to an increased risk of developing specific types of cancers.
Advances in Clinical Chemistry, Volume 86, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists.
Homeostasis and Toxicology of Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years.
Currently serving as a resource for the National Center for Toxological Research in their work with the Gulf Coast oil spill, this book presents current research conducted primarily by the airforce on the toxic effects of JP-8 jet fuel on the pulmonary, immune, dermal, and nervous systems.
The critically acclaimed laboratory standard for almost 50 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry.