Oxidative stress and aging Over the past several years there has been an extraordinarily rapid growth in our knowledge of free radical chemistry and its possible involvement in both normal essential biology and age- related disease and dysfunction.
This book is the first to be entirely devoted to the challenging art of handling membrane proteins out of their natural environment, a key process in biological and pharmaceutical research, but one plagued with difficulties and pitfalls.
Essentials of Medical Biochemistry, Second Edition: With Clinical Cases is the most condensed, yet detailed biochemistry overview available on the topic.
The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function.
This new edition provides a comprehensive look at themolecular genetics and biochemical basis of fungal biology, covering importantmodel organisms such as Aspergilli while also integrating advances made with zygomycetes and basidiomycetes.
Enzymes of Energy Technology, Volume 613 in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors.
Methods of Enzymatic Analysis, Volume 4 reviews developments in the use of enzymes as tools in analytical biochemistry, including advances in assay techniques.
Global yields of legumes have been relatively stagnant for the last five decades, despite the adoption of conventional and molecular breeding approaches.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.
Side Reactions in Peptide Synthesis, based on the author's academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis.
Chromatin Remodelling and Immunity, Volume 106, the latest release in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists.
The book summarizes the achievements of the past decade in the biochemistry, bioenergetics, structural and molecular biology of respiratory processes in selected genera of the domain Bacteria along with an extensive coverage of the redox chains of extremophiles belonging to the Archaean domain.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry.
The present new version of this popular laboratory manual is at the same time the first one of this text in the English language - and this makes me even a little proud, as it reminds me of probably the first collection of monoclonal recipes in English, written by myself, which circulated for a couple of years in many laboratories.
In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers' own research efforts- Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves- Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry
This volume provides the information needed to synthesize peptides by solid-phase synthesis (SPS) - employing polymeric support (resins), anchoring linkages (handles), coupling reagents (activators), and protection schemes.
For over fifty years the Methods in Enzymology series has been the critically aclaimed laboratory standard and one of the most respected publications in the field of biochemistry.
Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity.
Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature.
Ornithine Transcarbamylase: Basic Science and Clinical Considerations, written by a leading expert on OTC, for the first time assembles and analyzes more than 40 years of basic science and clinical research.
The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s).
From health and economic consequences to exposure assessment and detoxification, this reference comprehensively covers the formation, characteristics, and control of various toxins that occur in the production, storage, handling, and preparation of food.
Magnetic Tweezers for the Study of Protein Structure and Function, Volume 694 in the Methods in Enzymology serial highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Single membrane protein tethering for magnetic tweezer experiments, Membrane protein folding studies using a robust magnetic tweezer method, Magnetic tweezers in cell mechanics, and more.
This work establishes linear-scaling density-functional theory (DFT) as a powerful tool for understanding enzyme catalysis, one that can complement quantum mechanics/molecular mechanics (QM/MM) and molecular dynamics simulations.
This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world.
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies.
The Industry-University Cooperative Chemistry Program has sponsored seven previous international symposia covering a wide variety of topics of interest to industrial and academic chemists.
The purpose of this important monograph is to provide the reader with a better understanding of the toxicity, channels of absorption, and metabolism of explosives by the body.
Maximizing the potential of RNA interference in functional genomics - as well as in the development of therapeutics - continues to be at the forefront of biomedical research.
Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results.
Vaccination, chiefly responsible for the eradication of smallpox and the control of poliomyelitis and German measles in man and of foot-and- mouth, Marek's and Newcastle disease in domestic animals, remains the best answer to infectious diseases.
New approach for drug repurposing represents drug discovery and development which is a tedious process that requires 10-15 years of time, investments up to $1-2 billion, and have high risk of failure to enter into market for clinical applications.
This new volume emphasizes the drastic quantitative and qualitative transformation of our surrounding environment and looks at bioresource management and the tools needed to manageenvironmental stresses.
Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development.
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases.
This volume presents chapters that discuss secondary metabolites of marine origin, the industrial applications of phytochemicals, and recent advances in phytochemical research.
