100 Cases in Clinical Pharmacology, Therapeutics and Prescribing explores scenarios commonly seen by medical students and junior doctors in the ward, emergency department, outpatient clinic or in general practice in which an understanding of pharmacology and sound prescribing practice is central to successful clinical management and safe patient care.
The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio.
The most mysterious part of photosynthesis yet the most important for all aerobic life on Earth (including ourselves) is how green plants, algae and cyanobacteria make atmospheric oxygen from water.
The role of metal ions in protein folding and structure is a critical topic to a range of scientists in numerous fields, particularly those working in structural biology and bioinorganic chemistry, those studying protein folding and disease, and those involved in the molecular and cellular aspects of metals in biological systems.
For over fifty years the Methods in Enzymology series has been the critically aclaimed laboratory standard and one of the most respected publications in the field of biochemistry.
Addressing the numerous gaps in current information, Target Organ Toxicology in Marine and Freshwater Teleosts is an essential resource for researchers and professionals in aquatic toxicology and environmental risk assessment.
This book details several important medicinal plants, their occurrence, plant compounds and their chemical structures, and pharmacological properties against various human diseases.
The aim of this book is to bring together in one volume the current research and thought on the concept of membrane fluidity as a biological phenomenon.
Thymosins, the latest volume in the Vitamins and Hormones series, first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on thymosins research that spans new data from molecular biology to the clinic.
Environmental issues such as ozone layer depletion, overpopulation, biodiversity loss, global warming, natural resource depletion, and so on affect every organism on the planet somehow.
Carbohydrates are widely distributed in nature and widely available, and so are considered as a promising feedstock for the preparation of many organic chemical compounds.
Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research.
Vasopressin, Volume 113 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting updates on timely topics, including Diabetes Insipidus in Pregnancy, Vasopressin Inactivation: Role of Insulin-Regulated Aminopeptidase, Vasotocin and the Origins of the Vasopressin/Oxytocin Receptor Gene Family, Vasopressin V2 Receptor Ligand Recognition, Development and Therapeutic Potential of Vasopressin Synthetic Analog [V4Q5]dDAVP as a Novel Anticancer Agent, Cellular Junctions and Vasopressin, Vasopressin Actions in the Kidney Renin Angiotensin System and its Role in Hypertension and Renal Disease, Oxytocin/Vasopressin-Like Neuropeptide Signaling in Insects, and much more.
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets.
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 49 provides timely and pertinent information on a variety of timely topics, including Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Related to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis.
While adenosine triphosphate (ATP) is described as the universal currency of energy in all living organisms at the cellular level, the actual power lies in its phosphate tail.
This work is written to provide a qualitative introduction, appropriate for a general science audience, to the application of pragmagnetic resonance to the determination of biomolecular dynamics.
Rapid molecular identification and typing of micro-organisms is extremely important in efforts to monitor the geographical spread of virulent, epidemic or antibiotic-resistant pathogens.
Addresses the full gamut of questions in metalloprotein science Formatted as a question-and-answer guide, this book examines all major families of metal binding proteins, presenting our most current understanding of their structural, physicochemical, and functional properties.
Advances in Enzymology and Related Areas of Molecular Biology is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology.
Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences.
Divided into five parts, Microbial Food Contamination, Second Edition looks at emerging foodborne human pathogens andcomprehensively evaluates the microbiology, biochemistry, detection, risk, and threat of foodborne illness in today's global market.
Comprehensive Biomarker Discovery and Validation for Clinical Application provides the reader with an extensive introduction into all aspects of proteomics biomarker discovery, validation and development.
The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal.
Advanced Mechanical Models of DNA Elasticity includes coverage on 17 different DNA models and the role of elasticity in biological functions with extensive references.
The annual research conference for 1996 of the American Institute for Cancer Re- search was again held at the Loews L'Enfant Plaza Hotel in Washington, DC, August 29 and 30.
Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs.
This contributed volume on phytochemistry and pharmacology of the genus Bidens covers the chemical constituents and biological activities of this plant group in detail.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.
For 31 years, the North American Symbiotic Nitrogen Fixation Conference (for- merly Rhizobium Conference) has been a forum for scientists and graduate students to discuss their research advances, extending from basic aspects to agricultural appli- cations, and dealing with topics ranging from bacterial genetics and metabolism to plant genetics and physiology.
This book reviews the latest developments and applications in the field of biosensing, providing readers with an update of the earlier, successful edition, Biosensing for the 21st Century.
Antibodies protect us from a wide range of infectious diseases and cancers and have become an indispensable tool in science-both for conventional immune response research as well as other areas related to protein identification analysis.
Aflatoxins are responsible for damaging up to 25% of the world's food crops, resulting in large economic losses in developed countries and human and animal disease in under-developed ones.
Specifically focusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference provides a comprehensive overview of cutting-edge research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors-an