This book describes analysis techniques and results of topics such as physical backgrounds, chemical backgrounds, and principal methods of topo-optical reactions used in ultrastructure research of the ECM; orientation patterns of GAGs and collagen in different tissues/cartilage, cornea, kidney basement membranes, and skin; factors involved in the formation of submicroscopically ordered matrix structure; and cell-matrix interactions, including cytoskeleton-cell-membrane-matrix relationships.
This volume covers protocols related to both pluripotent and somatic stem cells, including the ethical procurement of tissues and cells for the provision of "e;seed stock,"e; standardized methods for deriving hESCs and iPSCs, isolating mesenchymal stem cells, cell culture and cryopreservation, in addition to quality assurance and information management.
The dangers and drawbacks inherent in radioactivity-based methods along with a demonstrated and dramatic increase in sensitivity have precipitated a major shift towards luminescence measurements and visualization techniques.
Nuclear Magnetic Resonance spectroscopy is a dynamic way for scientists of all kinds to investigate the physical, chemical, and biological properties of matter.
Endocytosis and vesicular trafficking determine the landscape of the cell's exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers.
Endocrine Pathology integrates classical diagnostic anatomic pathology with recent developments in immunochemistry and molecular biology in its approach to endocrine disorders.
This is the first in a two-volume, comprehensive treatment of the methodologies used in researching the Zebrafish, an emerging vertebrate model system.
This book presents the latest advances concerning the regulation of chromosome segregation during cell division by means of centromeres and kinetochores.
This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance protein-protein recognition, and to build upon nature's cyclic peptides and macrocycles.
Focussing on China's stem cell research, this book investigates how, over the last decade, Chinese scientists, ethicists and policy-makers have developed a cosmopolitan sensibility in comprehending and responding to ethical and regulatory concerns.
This book discusses central concepts and theories in cell biology from the ancient past to the 21st century, based on the premise that understanding the works of scientists like Hooke, Hofmeister, Caspary, Strasburger, Sachs, Schleiden, Schwann, Mendel, Nemec, McClintock, etc.
Animal Models of Disease, Part C, Volume 192 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors, The current models unravel the molecular mechanisms underlying the intricate pathophysiology of Alzheimer's disease using Zebrafish, Colitis mouse model, Matching model with mechanism: appropriate animal models for studying various aspects of diabetes pathophysiology, Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics, and much more.
The book is a multi-authored book of 18 chapters comprising the state of the art work of all relevant topics on modern fish histology from 28 authors from ten countries.
A useful reference for those using or interested in cultured invertebrate cells, this two-volume text provides information about techniques and advances in invertebrate tissue culture.
This volume covers data describing the role of free radicals and antioxidants in respiratory disorders, including the data that deal with clinical and pre-clinical trials.
The Immortal Germline, Volume 135 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Balbiani body, germ plasm and polarity, Wolbachia and the germline, Human germ line biology, Reproduction/immunity and sperm success, Mammalian spermatogenesis, Reproduction/regeneration and germ cells in planarians, Germline stem cell homeostasis, Germline soma interactions/sex determination, Reconstituting the mouse germ-cell specification pathway in vitro, Maternal Germ line inheritance of mitochondria, Transposon strategies, and more.
Using as a theme the encounter between protozoan parasites and macrophages, this volume brings together cell biologists, immunologists and protozoologists to review current developments in this broad and dynamic research area.
This book describes the recent advancement of basic research on the biology of aging and longevity studies in various organisms, as well as the neurobiology of aging and neurodegeneration mechanisms.
Gonadotropins: From Bench Side to Bedside, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on all aspects of gonadotropins, from research to treatment.
This book aims to cover the knowledge of protein folding accumulated from studies of disulfide-containing proteins, including methodologies, folding pathways, and folding mechanism of numerous extensively characterized disulfide proteins.
This book focuses on the study of how the properties of nanodiscs, such as lipid composition and size, influence the function of the embedding integral membrane protein, bacteriorhodopsin.
This book addresses one of the major challenges of immunology today that is being directed to the translation of the rapidly emerging volume of basic science contributions of immunology to clinical medicine.
