This book presents a collection of expert reviews on different subcellular compartments of the cardiomyocyte, addressing fundamental questions such as how these compartments are assembled during development, how they are changed in and by disease and which signaling pathways have been implicated in these processes so far.
Protein kinase CK2 (formerly casein kinase II or 2) is known to play a critical role in the control of cell growth and cell death and is thus intimately involved in the development of cancer.
This book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis.
The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.
Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse.
Consists of critical reviews and original research papers from the 2014 International Symposium on the "e;Biochemical Role of Eukaryotic Cell Surface Macromolecules"e;.
This book offers clear, up-to-date guidance on how to report cytologic findings in cervical, vaginal and anal samples in accordance with the 2014 Bethesda System Update.
This book explores critical principles and new concepts in bioengineering, integrating the biological, physical and chemical laws and principles that provide a foundation for the field.
This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein.
This book reviews the current state of information on reactive oxygen and nitrogen species and their role in cell communication during plant growth, development and adaptation to stress conditions.
Respiratory allergy is constantly encountered and is sharply on the rise, particularly in the two most vulnerable age-groups: young children and seniors.
This volume describes the state-of-knowledge in the study of the relationships between mechanical loading states in tissues and common pathophysiologies related to increase in mass of adipose tissues and/or hyperglycemia which eventually lead to obesity, diabetes, insulin resistance, hyperlipidemia, metabolic inflammations, certain types of cancer and other related diseases.
The Short QT Syndrome (SQTS) is characterized by abbreviated QT intervals on the electrocardiogram, increased risk of cardiac arrhythmias and sudden death.
During the second half of the 20th century, the introduction of a variety of new techniques greatly expanded our knowledge of the structure of nerve and neuroglial cells and of the organization of the nervous system at the cellular level.
This SpringerBrief explores the physiological roles of Skp1-Cullin1-F-box Complex (SCF) and Anaphase Promoting Complex (APC) in normal cells and in tumor formation.
Like many fields of science, the future of medicine is frequently predicted by the science fiction writers of today, very much as many of today's medical advances were presaged by science fiction stories of the past.
The objective of this book is to present the strategies employed by living organisms on a molecular level and to help understand the basics of Systems Biology.
The period between 1950 and 1980 were the golden unique insights into how pathological processes affect years of transmission electron microscopy and produced cell organization.